Next departures for Orlando to Indianapolis on December 15
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Orlando Bus Station
Downtown Transit Center
Cheapest
Bus
Orlando Bus Station
Indianapolis Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Bus
Orlando Bus Station
Downtown Transit Center
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Next departures for Orlando to Indianapolis on December 17
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Orlando Bus Station
Downtown Transit Center
Cheapest
Bus
Orlando Bus Station
Indianapolis Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Bus
Orlando Bus Station
Downtown Transit Center
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Next departures for Orlando to Indianapolis on December 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
Cheapest
Bus
Orlando Bus Station
Indianapolis Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Bus
Orlando Bus Station
Downtown Transit Center
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Next departures for Orlando to Indianapolis on December 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
Cheapest
Bus
Orlando Bus Station
Indianapolis Bus Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Bus
Orlando Bus Station
Downtown Transit Center
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Next departures for Orlando to Indianapolis on December 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Orlando Bus Station
Indianapolis Bus Station
CheapestFastest
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Bus
Orlando Bus Station
Downtown Transit Center
No tags
FlixBus + Greyhound Lines, Inc.
Bus
Orlando Bus Station
Indianapolis Bus Station
No tags
Bus
Orlando Bus Station
Downtown Transit Center
No tags
Last refresh of the prices: Yesterday at 4:23 PM EST.
Compare 2 ways to go from Orlando to Indianapolis
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 22 hours 5 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Orlando to Indianapolis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Orlando to Indianapolis?
The cheapest bus tickets from Orlando to Indianapolis start from $88. The average price for this route is around $164. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Orlando to Indianapolis?
The average bus trip duration from Orlando to Indianapolis is 22h 5m, covering a distance of 820 miles (1322 km). The quickest bus can get you there in 19h 55m and is operated by Greyhound.
Which bus companies service the Orlando to Indianapolis route?
Several major bus companies operate on this route with 10 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Orlando to Indianapolis?
The earliest bus departs from Orlando to Indianapolis at 5:15am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Orlando to Indianapolis?
A bus trip from Orlando to Indianapolis generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Orlando to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.
Which bus company has the best Wi-Fi from Orlando to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Orlando to Indianapolis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Orlando to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/13
$112
12/14
$180
Today
$164
12/16
No data
12/17
$114
12/18
$123
12/19
$136
12/20
$149
The cheapest trip from Orlando to Indianapolis was searched and found on Dec 13, 2025 with a price of $112
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Indianapolis, as early as possible.
You can expect to pay from $112 to $230 for a bus ticket from Orlando to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $114 which is on 2025-12-17.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Orlando to Indianapolis?
The bus is the cheapest travel choice for this destination