Bus Tickets from Milano to Syracuse

Next departures

Next departures for Milano to Syracuse on September 8
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Flixbus
Lampugnano bus station
Terminal InterbusCheapestFastest
Flixbus
Lampugnano bus station
Terminal InterbusNo tags
Flixbus
Milan (San Donato M3)
Terminal InterbusNo tags
Flixbus
Milan (Assago M2)
Terminal InterbusNo tags
Flixbus
Via Luigi Cadorna
Terminal InterbusNo tags

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Milano to Syracuse.

Bus
Average Price$58 - $206Average Duration1d 3h
26kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$305 - $305Average Duration22h 41m
26kg CO₂e5 out of 5 stars
Carpool
Average Price$120 - $120Average Duration15h 40m
45kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Milano to Syracuse

Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 1 day, 3 hours 10 minutes and with fares starting at just $58, it presents an excellent value for a comfortable ride.

6bus per day
1d 3hAverage Duration
$58Cheapest ticket
26kgCO₂ emissions

Bus Milano to Syracuse: Trip Overview

Average ticket price$99
Average bus trip duration1d 3h
Number of daily buses6
Earliest bus departure12:55pm
Distance656 miles (1057 km)
Latest bus departure9:30pm

Milano to Syracuse Bus

With Busbud, comparing and booking tickets for a bus from Milano to Syracuse is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Milano to Syracuse.

Discover how much the bus trip from Milano to Syracuse will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Milano - Syracuse

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/06
$83
09/07
$78
Today
$95
09/09
$66
09/10
$61
09/11
$74
09/12
$77
09/13
$72
busbud logoThe cheapest trip from Milano to Syracuse was searched and found on Sep 10, 2025 with a price of $61

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Syracuse, as early as possible.

You can expect to pay from $61 to $128 for a bus ticket from Milano to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at $61 which is on 2025-09-10.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Milano to Syracuse.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Milano to Syracuse.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Milano to Syracuse will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Milano to Syracuse, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

What's the cheapest way to go from Milano to Syracuse?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Milano by bus?

Bus from Syracuse to Milano

You can also go to Syracuse by train

Train from Milano to Syracuse

Why choose Busbud?

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