Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mezcales Central Bus Station | Puebla Central Bus Station | CheapestFastest | ||||
 | Bus | Nogales Av. Alvaro Obregon | Puebla Central Bus Station | No tags |
Last refresh of the prices: Today at 12:38 PM CST.
Get from Mezcales to Puebla
The journey takes about 17 hours 5 minutes and with fares starting at just $135, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mezcales and Puebla?
Stops in Mezcales
- A
Parada de Autobuses de Mezcales
Carretera Vallarta-Tepic # 210 , Colonia Ica, Menchaca, 63150 Tepic, Nay.
Stops in Puebla
- A
Terminal de Autobuses
Blvd. Norte No. 4222 (Col. Las Cuartillas), 72080 Puebla - B
Blvd. Carmen Serdán & Calle 27 Nte.
Blvd. Carmen Serdán & Calle 27 Nte., Sta María la Rivera, 72010 Puebla, Pue., Mexico
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Frequently asked questions about traveling from Mezcales to Puebla, PUE by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Mezcales to Puebla?
The cheapest bus tickets from Mezcales to Puebla start from $135. The average price for this route is around $143. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Mezcales to Puebla?
The average bus trip duration from Mezcales to Puebla is 17h 5m, covering a distance of 473 miles (763 km). The quickest bus can get you there in 13h 55m and is operated by Pacifico.
Which bus companies service the Mezcales to Puebla route?
Several major bus companies operate on this route with 2 buses available per day, including services from Futura, Chihuahuenses, Pacifico.
What is the earliest and latest departure time for the bus from Mezcales to Puebla?
The earliest bus departs from Mezcales to Puebla at 1:45pm. And the latest bus departs at 10:16pm.
What are the CO₂ emissions for the bus trip from Mezcales to Puebla?
A bus trip from Mezcales to Puebla generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Mezcales to Puebla?
According to Busbud customers, the highest-rated bus company on this route is Futura, with an average rating of 3.4 out of 5 stars based on 763 reviews.
Which bus company has the best Wi-Fi from Mezcales to Puebla?
Based on reviews on Busbud, the bus company Chihuahuenses has the best Wi-Fi rating with a score of 1.8.
Which bus company has the most timely service from Mezcales to Puebla?
According to Busbud traveler reviews, the most timely bus company on this route is Pacifico, with a punctuality rating of 3.0 out of 5 stars.
Which bus company has the cleanest buses from Mezcales to Puebla?
According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Futura, with a cleanliness rating of 3.9 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mezcales to Puebla, PUE was searched and found on Jan 30, 2026 with a price of $145To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mezcales to Puebla, PUE, as early as possible.
You can expect to pay from $145 to $264 for a bus ticket from Mezcales to Puebla, PUE based on the last 2 days. You can expect to find the cheapest price for the trip at $145 which is on 2026-01-30.
Usually Chihuahuenses will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
