Bus Tickets from Mexico City to Santiago Tuxtla

Find affordable bus tickets from Mexico City to Santiago Tuxtla with flexible options. Book your trip now

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TodayJun 23
from $63
TomorrowJun 24
from $74
WedJun 25
ThuJun 26
from $74
FriJun 27
from $63
SatJun 28
SunJun 29
MonJun 30

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 24 at
    Departure city: Mexico City
    Departure location: TAPO
    Arrival time: June 25 at
    Destination city: Santiago Tuxtla
    Destination location: Santiago Tuxtla, Santiago Tuxtla Ver.
    Operated by: ADOADO
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Mexico City
    Departure location: TAPO
    Arrival time: June 25 at
    Destination city: Santiago Tuxtla
    Destination location: Santiago Tuxtla, Santiago Tuxtla Ver.
    Operated by: ADOADO
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Mexico City
    Departure location: TAPO
    Arrival time: June 25 at
    Destination city: Santiago Tuxtla
    Destination location: Santiago Tuxtla, Santiago Tuxtla Ver.
    Operated by: ADOADO
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Mexico City
    Departure location: Terminal del Norte
    Arrival time: June 25 at
    Destination city: Santiago Tuxtla
    Destination location: Santiago Tuxtla, Santiago Tuxtla Ver.
    Operated by: ADOADO
    Vehicle: BusDuration:
  • Departure time: June 24 at
    Departure city: Mexico City
    Departure location: Terminal del Norte
    Arrival time: June 25 at
    Destination city: Santiago Tuxtla
    Destination location: Santiago Tuxtla, Santiago Tuxtla Ver.
    Operated by: ADOADO
    Vehicle: BusDuration:

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Bus Mexico City to Santiago Tuxtla: Trip Overview

Average ticket price$74
Average bus trip duration9h
Number of daily buses5.217391304347826
Earliest bus departure8:00pm
Distance258 miles (415 km)
Latest bus departure11:59pm

Mexico City to Santiago Tuxtla Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mexico City to Santiago Tuxtla.

Bus service from Mexico City to Santiago Tuxtla will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Santiago Tuxtla from Mexico City, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Mexico City - Santiago Tuxtla

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/21
$65
06/22
$64
Today
$55
06/24
$64
06/25
No data
06/26
$64
06/27
$55
06/28
$64
busbud logoThe cheapest trip from Mexico City to Santiago Tuxtla was searched and found on Jun 23, 2025 with a price of $55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexico City to Santiago Tuxtla, as early as possible.

You can expect to pay from $55 to $65 for a bus ticket from Mexico City to Santiago Tuxtla based on the last 2 days. You can expect to find the cheapest price for the trip at $55 which is on 2025-06-27.

Usually ADO will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mexico City to Santiago Tuxtla but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Mexico City to Santiago Tuxtla, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Mexico City to Santiago Tuxtla.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mexico City to Santiago Tuxtla.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Mexico City by bus?

Bus from Mexico City to Santiago Tuxtla

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