Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Meridian Bus Station | Tupelo (Brothers Quick Stop) | Cheapest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Meridian Bus Station | Tupelo (Brothers Quick Stop) | Fastest |
Last refresh of the prices: Today at 8:47 AM CST.
Get from Meridian to Tupelo
The journey takes about 12 hours 15 minutes and with fares starting at just $55, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Meridian to Tupelo by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Meridian to Tupelo?
The cheapest bus tickets from Meridian to Tupelo start from $55. The average price for this route is around $73. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Meridian to Tupelo?
The average bus trip duration from Meridian to Tupelo is 12h 15m, covering a distance of 130 miles (209 km). The quickest bus can get you there in 12h 15m and is operated by Greyhound.
Which bus companies service the Meridian to Tupelo route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Meridian to Tupelo?
The earliest bus departs from Meridian to Tupelo at 2:45am. And the latest bus departs at 10:50am.
What are the CO₂ emissions for the bus trip from Meridian to Tupelo?
A bus trip from Meridian to Tupelo generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Meridian to Tupelo was searched and found on Jan 17, 2026 with a price of $76To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Meridian to Tupelo, as early as possible.
You can expect to pay from $76 to $76 for a bus ticket from Meridian to Tupelo based on the last 2 days. You can expect to find the cheapest price for the trip at $76 which is on 2026-01-17.
