Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Memphis Bus Station | Des Moines | CheapestFastest |
Last refresh of the prices: Last Saturday at 6:13 PM CST.
Get from Memphis to Des Moines
The journey takes about 19 hours 55 minutes and with fares starting at just $134, it presents an excellent value for a comfortable ride.
Where are the popular stops in Memphis and Des Moines?
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Frequently asked questions about traveling from Memphis, TN to Des Moines by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Memphis to Des Moines?
The cheapest bus tickets from Memphis to Des Moines start from $134. The average price for this route is around $159. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Memphis to Des Moines?
The average bus trip duration from Memphis to Des Moines is 19h 55m, covering a distance of 493 miles (795 km). The quickest bus can get you there in 14h 45m and is operated by Jefferson Lines.
Which bus companies service the Memphis to Des Moines route?
Several major bus companies operate on this route with 1 buses available per day, including services from Greyhound, Jefferson Lines.
What is the earliest and latest departure time for the bus from Memphis to Des Moines?
The earliest bus departs from Memphis to Des Moines at 8:30am. And the latest bus departs at 6:40pm.
What are the CO₂ emissions for the bus trip from Memphis to Des Moines?
A bus trip from Memphis to Des Moines generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Memphis to Des Moines?
According to Busbud customers, the highest-rated bus company on this route is Jefferson Lines, with an average rating of 3.9 out of 5 stars based on 764 reviews.
Which bus company has the best Wi-Fi from Memphis to Des Moines?
Based on reviews on Busbud, the bus company Greyhound has the best Wi-Fi rating with a score of 2.4.
Which bus company has the most timely service from Memphis to Des Moines?
According to Busbud traveller reviews, the most timely bus company on this route is Jefferson Lines, with a punctuality rating of 3.5 out of 5 stars.
Which bus company has the cleanest buses from Memphis to Des Moines?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Jefferson Lines, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Memphis, TN to Des Moines was searched and found on Jan 14, 2026 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Memphis, TN to Des Moines, as early as possible.
You can expect to pay from $121 to $151 for a bus ticket from Memphis, TN to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2026-01-14.
