Bus Tickets from Lyon to Mainz

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Previously seen trips

One passenger / one way

  • Departure time: December 21 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: December 22 at
    Destination city: Mainz
    Destination location: Mainz
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: December 21 at
    Departure city: Lyon
    Departure location: Aéroport LYS
    Arrival time: December 22 at
    Destination city: Mainz
    Destination location: Mainz
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: December 21 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: December 22 at
    Destination city: Mainz
    Destination location: Mainz
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: December 21 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: December 22 at
    Destination city: Mainz
    Destination location: Mainz
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: December 21 at
    Departure city: Lyon
    Departure location: Perrache
    Arrival time: December 22 at
    Destination city: Mainz
    Destination location: Mainz
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Lyon to Mainz.

Bus
Average Price$54 - $112Average Duration18h 10m
13kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average Price$45 - $45Average Duration7h 20m
22kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from Lyon to Mainz

Among the sustainable travel choices, the bus stands out as the good way to reach Mainz. The journey takes about 18 hours 10 minutes and with fares starting at just $54, it presents an excellent value for a comfortable ride.

11bus per day
18h 10mAverage Duration
$54Cheapest ticket
13kgCO₂ emissions

Bus Lyon to Mainz: Trip Overview

Average ticket price$70
Average bus trip duration18h 10m
Number of daily buses11
Earliest bus departure2:25am
Distance330 miles (532 km)
Latest bus departure11:40pm

Lyon to Mainz Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Lyon to Mainz.

Bus service from Lyon to Mainz will be provided by the most trusted bus companies.

Discover how much the bus trip from Lyon to Mainz will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Lyon - Mainz

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/27
$56
08/28
$55
Today
No data
08/30
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08/31
No data
09/01
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09/02
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09/03
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busbud logoThe cheapest trip from Lyon to Mainz was searched and found on Aug 28, 2025 with a price of $55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Mainz, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Lyon to Mainz but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Lyon to Mainz, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lyon to Mainz will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Lyon to Mainz, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Lyon by bus?

Bus from Mainz to Lyon

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