Bus Tickets from Lyon to Mainz

Compare 2 ways to go from Lyon to Mainz

Bus
Average PriceUS$54 - US$112Average Duration18h 10m
13kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average PriceUS$45 - US$45Average Duration7h 20m
22kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the bus from Lyon to Mainz

Among the sustainable travel choices, the bus stands out as a good way to reach Mainz. The journey takes about 18 hours 10 minutes, and with fares starting at just US$54, it presents an excellent value for a comfortable ride.

11bus per day
18h 10mAverage Duration
US$54Cheapest ticket
13kgCO₂ emissions

Bus Lyon to Mainz: Trip Overview

Average Ticket PriceUS$70
Average Bus Trip Duration18h 10m
Number of daily buses11
Earliest bus departure2:25am
Distance532 km
Latest bus departure11:40pm

Lyon to Mainz Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Lyon to Mainz.

Bus service from Lyon to Mainz will be provided by the most trusted bus companies.

Discover how much the bus trip from Lyon to Mainz will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Lyon - Mainz

  1. What is the distance between Lyon and Mainz?

    Lyon and Mainz are 537 km (333 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Lyon to Mainz?

    Buses departing from Perrache in Lyon will take you to Mainz in Mainz.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-27
US$56
08-28
US$55
Today
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08-30
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08-31
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09-01
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busbud logoThe cheapest trip from Lyon to Mainz was searched and found on Aug 28, 2025 with a price of US$55

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Mainz, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Lyon to Mainz but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from Lyon to Mainz, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Lyon to Mainz will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Lyon to Mainz, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Lyon by bus?

Bus from Mainz to Lyon

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