Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Key West Bus Station | Melbourne (Mobil Gas Station) | CheapestFastest |
Last refresh of the prices: Last Sunday at 1:26 PM EST.
Get from Key West to Melbourne
The journey takes about 10 hours 30 minutes and with fares starting at just $67, it presents an excellent value for a comfortable ride.
Where are the popular stops in Key West and Melbourne?
Stops in Key West
- A908 Caroline St, Key West, FL 33040, USA
- B
EYW Airport
3535 Florida A1A, Key West, FL 33040, USA
Stops in Melbourne
- A
Melbourne Bus Stop - Waffle House
4650 W New Haven Ave, Melbourne, FL 32904 - B4600 W New Haven Ave, Melbourne, FL 32901, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Key West to Melbourne, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Key West to Melbourne?
The cheapest bus tickets from Key West to Melbourne start from $67. The average price for this route is around $67. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Key West to Melbourne?
The average bus trip duration from Key West to Melbourne is 10h 30m, covering a distance of 260 miles (419 km). The quickest bus can get you there in 10h 30m and is operated by Greyhound.
Which bus companies service the Key West to Melbourne route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Key West to Melbourne?
The earliest bus departs from Key West to Melbourne at 10:00am. And the latest bus departs at 10:00am.
What are the CO₂ emissions for the bus trip from Key West to Melbourne?
A bus trip from Key West to Melbourne generates an estimated 10 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Key West to Melbourne, US was searched and found on Jan 18, 2026 with a price of $60To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Key West to Melbourne, US, as early as possible.
You can expect to pay from $60 to $60 for a bus ticket from Key West to Melbourne, US based on the last 2 days. You can expect to find the cheapest price for the trip at $60 which is on 2026-01-18.
