Bus Tickets from Jefferson City, MO to Indianapolis

Compare 2 ways to go from Jefferson City to Indianapolis.

Bus
Average Price$39 - $125Average Duration16h 40m
13kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$169 - $169Average Duration14h 11m
49kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Jefferson City to Indianapolis

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 16 hours 40 minutes and with fares starting at just $39, it presents an excellent value for a comfortable ride.

2bus per day
16h 40mAverage Duration
$39Cheapest ticket
13kgCO₂ emissions

Bus Jefferson City, MO to Indianapolis: Trip Overview

Average ticket price$66
Average bus trip duration16h 40m
Number of daily buses2
Earliest bus departure7:15pm
Distance331 miles (533 km)

Jefferson City to Indianapolis Bus

With Busbud, comparing and booking tickets for a bus from Jefferson City to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Jefferson City to Indianapolis.

From cheap bus tickets to more luxurious buses traveling from Jefferson City to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Jefferson City, MO - Indianapolis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/28
No data
08/29
No data
Today
No data
08/31
No data
09/01
$57
09/02
No data
09/03
$31
09/04
No data
busbud logoThe cheapest trip from Jefferson City, MO to Indianapolis was searched and found on Sep 3, 2025 with a price of $31

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jefferson City, MO to Indianapolis, as early as possible.

You can expect to pay from $31 to $57 for a bus ticket from Jefferson City, MO to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $31 which is on 2025-09-03.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Jefferson City to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Jefferson City to Indianapolis.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Jefferson City to Indianapolis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Jefferson City to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

What's the cheapest way to go from Jefferson City, MO to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jefferson City, MO by bus?

Bus from Indianapolis to Jefferson City, MO

Why choose Busbud?

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Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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