Bus Tickets from Jacksonville, FL to Indianapolis

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TodaySep 3
from $143
TomorrowSep 4
from $114
FriSep 5
SatSep 6
from $117
SunSep 7
from $105
MonSep 8
from $89
TueSep 9
WedSep 10
from $86

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: September 4 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: September 4 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: September 4 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: September 5 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Compare 2 ways to go from Jacksonville to Indianapolis.

Bus
Average Price$88 - $254Average Duration22h 50m
28kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$221 - $473Average Duration1d 12h
102kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Indianapolis

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 22 hours 50 minutes and with fares starting at just $88, it presents an excellent value for a comfortable ride.

9bus per day
22h 50mAverage Duration
$88Cheapest ticket
28kgCO₂ emissions

Bus Jacksonville, FL to Indianapolis: Trip Overview

Average ticket price$116
Average bus trip duration22h 50m
Number of daily buses9
Earliest bus departure8:05am
Distance698 miles (1125 km)
Latest bus departure9:45pm

Jacksonville to Indianapolis Bus

Busbud helps you find a bus from Jacksonville to Indianapolis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Jacksonville to Indianapolis from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Jacksonville to Indianapolis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Jacksonville, FL - Indianapolis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
09/01
$159
09/02
$165
Today
$178
09/04
$109
09/05
No data
09/06
$112
09/07
$123
09/08
$82
busbud logoThe cheapest trip from Jacksonville, FL to Indianapolis was searched and found on Sep 8, 2025 with a price of $82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Indianapolis, as early as possible.

You can expect to pay from $82 to $221 for a bus ticket from Jacksonville, FL to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $82 which is on 2025-09-08.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Jacksonville and Indianapolis!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Indianapolis, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Jacksonville to Indianapolis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Jacksonville to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Jacksonville, FL to Indianapolis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from Indianapolis to Jacksonville, FL

You can also go to Indianapolis by train

Train from Jacksonville, FL to Indianapolis

Why choose Busbud?

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Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

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