Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Jackson (MI) Bus Station | Gateway Station | No tags | ||||
| Bus | Jackson (MI) Bus Station | Gateway Station | No tags | ||||
| Bus | Jackson (MI) Bus Station | Gateway Station | No tags | ||||
| Bus | Jackson (MI) Bus Station | Gateway Station | No tags | ||||
| Bus | Jackson (MI) Bus Station | Gateway Station | No tags |
Compare 2 ways to go from Jackson to St. Louis
Among the sustainable travel choices, the Train stands out as the good way to reach St. Louis. The journey takes about 12 hours 25 minutes and with fares starting at just $102, it presents an excellent value for a comfortable ride.
Where are the popular stops in Jackson and St. Louis?
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Jackson, MI, US to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Jackson to St. Louis?
The cheapest bus tickets from Jackson to St. Louis start from $111. The average price for this route is around $124. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Jackson to St. Louis?
The average bus trip duration from Jackson to St. Louis is 14h 40m, covering a distance of 394 miles (635 km). The quickest bus can get you there in 14h 10m and is operated by Greyhound.
Which bus companies service the Jackson to St. Louis route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Jackson to St. Louis?
The earliest bus departs from Jackson to St. Louis at 1:30am. And the latest bus departs at 12:40pm.
What are the CO₂ emissions for the bus trip from Jackson to St. Louis?
A bus trip from Jackson to St. Louis generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jackson, MI, US to St. Louis was searched and found on Jan 16, 2026 with a price of $103To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jackson, MI, US to St. Louis, as early as possible.
You can expect to pay from $103 to $104 for a bus ticket from Jackson, MI, US to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $103 which is on 2026-01-16.
What's the cheapest way to go from Jackson, MI, US to St. Louis?
The Bus is the cheapest travel choice for this destination
