Bus Indianapolis to Jacksonville from $92 | Compare & Save up to 60%

Next departures

Next departures for Indianapolis to Jacksonville on March 19
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	6:25pm	Downtown Transit Center	19h 10m	1:35pm	Jacksonville Bus Station	CheapestFastest
Greyhound Lines, Inc. + FlixBus	4:05pm	Indianapolis Bus Station	21h 30m	1:35pm	Jacksonville Bus Station	No tags
	8:10pm	Indianapolis Bus Station	23h 45m	7:55pm	Jacksonville Bus Station	No tags
FlixBus + Greyhound Lines, Inc.	11:30pm	Downtown Transit Center	20h 25m	7:55pm	Jacksonville Bus Station	No tags

Next departures for Indianapolis to Jacksonville on March 20
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	11:15am	Indianapolis Bus Station	19h 45m	7:00am	Jacksonville Bus Station	Cheapest
	6:25pm	Downtown Transit Center	19h 10m	1:35pm	Jacksonville Bus Station	Fastest
	10:50am	Greyhound Amtrak Station	1d 19h	6:32am	Jacksonville Amtrak Station	No tags
Greyhound Lines, Inc. + FlixBus	4:05pm	Indianapolis Bus Station	21h 30m	1:35pm	Jacksonville Bus Station	No tags
	8:10pm	Indianapolis Bus Station	23h 45m	7:55pm	Jacksonville Bus Station	No tags

Next departures for Indianapolis to Jacksonville on March 21
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	12:15am	Downtown Transit Center	1d 11h	11:30am	Jacksonville Bus Station	Cheapest
	6:25pm	Downtown Transit Center	19h 10m	1:35pm	Jacksonville Bus Station	Fastest
	10:50am	Greyhound Amtrak Station	1d 19h	6:32am	Jacksonville Amtrak Station	No tags
Greyhound Lines, Inc. + FlixBus	11:15am	Indianapolis Bus Station	19h 45m	7:00am	Jacksonville Bus Station	No tags
	8:10pm	Indianapolis Bus Station	23h 45m	7:55pm	Jacksonville Bus Station	No tags

Next departures for Indianapolis to Jacksonville on March 22
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	4:05pm	Indianapolis Bus Station	21h 30m	1:35pm	Jacksonville Bus Station	Cheapest
	6:25pm	Downtown Transit Center	19h 10m	1:35pm	Jacksonville Bus Station	Fastest
	10:50am	Greyhound Amtrak Station	1d 19h	6:32am	Jacksonville Amtrak Station	No tags
Greyhound Lines, Inc. + FlixBus	11:15am	Indianapolis Bus Station	19h 45m	7:00am	Jacksonville Bus Station	No tags
	8:10pm	Indianapolis Bus Station	23h 45m	7:55pm	Jacksonville Bus Station	No tags

Next departures for Indianapolis to Jacksonville on March 23
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	11:15am	Indianapolis Bus Station	19h 45m	7:00am	Jacksonville Bus Station	Cheapest
	6:25pm	Downtown Transit Center	19h 10m	1:35pm	Jacksonville Bus Station	Fastest
	10:50am	Greyhound Amtrak Station	1d 19h	6:32am	Jacksonville Amtrak Station	No tags
Greyhound Lines, Inc. + FlixBus	4:05pm	Indianapolis Bus Station	21h 30m	1:35pm	Jacksonville Bus Station	No tags
	8:10pm	Indianapolis Bus Station	23h 45m	7:55pm	Jacksonville Bus Station	No tags

Next departures for Indianapolis to Jacksonville on March 24
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	11:15am	Indianapolis Bus Station	19h 45m	7:00am	Jacksonville Bus Station	Cheapest
	6:25pm	Downtown Transit Center	19h 10m	1:35pm	Jacksonville Bus Station	Fastest
	10:50am	Greyhound Amtrak Station	1d 19h	6:32am	Jacksonville Amtrak Station	No tags
Greyhound Lines, Inc. + FlixBus	4:05pm	Indianapolis Bus Station	21h 30m	1:35pm	Jacksonville Bus Station	No tags
	8:10pm	Indianapolis Bus Station	23h 45m	7:55pm	Jacksonville Bus Station	No tags

Next departures for Indianapolis to Jacksonville on March 25
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	4:05pm	Indianapolis Bus Station	21h 30m	1:35pm	Jacksonville Bus Station	Cheapest
	6:25pm	Downtown Transit Center	19h 10m	1:35pm	Jacksonville Bus Station	Fastest
	10:50am	Greyhound Amtrak Station	1d 19h	6:32am	Jacksonville Amtrak Station	No tags
Greyhound Lines, Inc. + FlixBus	11:15am	Indianapolis Bus Station	19h 45m	7:00am	Jacksonville Bus Station	No tags
	8:10pm	Indianapolis Bus Station	23h 45m	7:55pm	Jacksonville Bus Station	No tags

Last refresh of the prices: Today at 1:19 AM EDT.

Where are the popular stops in Indianapolis and Jacksonville?

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Stops in Jacksonville

A
Jacksonville Amtrak Station
3570 Clifford Ln, Jacksonville, FL 32209, USA
Visit page
B
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA
C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207
D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

03/17

No data

03/18

$192

Today

$181

03/20

$223

03/21

$207

03/22

$172

03/23

$127

03/24

$119

The cheapest trip from Indianapolis to Jacksonville, FL was searched and found on Mar 24, 2026 with a price of $119

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Jacksonville, FL, as early as possible.

You can expect to pay from $119 to $1,503 for a bus ticket from Indianapolis to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $119 which is on 2026-03-24.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.