Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Downtown Transit Center | Des Moines (Subway) | CheapestFastest | |||||
 | Indianapolis Bus Station | Des Moines (Subway) | No tags |
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Bus Indianapolis to Des Moines: Trip Overview
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Indianapolis to Des Moines Bus
With Busbud, comparing and booking tickets for a bus from Indianapolis to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Indianapolis to Des Moines.
Discover how much the bus trip from Indianapolis to Des Moines will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Indianapolis and Des Moines?
Frequently asked questions for your trip Indianapolis - Des Moines
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Des Moines was searched and found on Sep 17, 2025 with a price of $69To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Des Moines, as early as possible.
You can expect to pay from $69 to $76 for a bus ticket from Indianapolis to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-09-17.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while traveling from Indianapolis to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Indianapolis to Des Moines.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Indianapolis to Des Moines will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Indianapolis to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Top traveled bus routes
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Popular Buses Connecting Indianapolis
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Popular Buses Connecting Des Moines
Buses Leaving from Des Moines
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Buses Going to Des Moines
- Bus from Washington to Des Moines
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- Bus St. Louis - Des Moines
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- Bus from Cedar Rapids to Des Moines
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Popular routes in this country
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