Next departures for Indianapolis to Boston on December 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Brookline
Cheapest
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Boston (South Station)
Fastest
Greyhound Amtrak Station
South Station (Train Terminal)
No tags
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
Boston (South Station)
No tags
Indianapolis Bus Station
Boston (South Station)
No tags
Next departures for Indianapolis to Boston on December 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
Brookline
Cheapest
Downtown Transit Center
151 Steel Pl, Cambridge
Fastest
Greyhound Amtrak Station
South Station (Train Terminal)
No tags
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
Boston (South Station)
No tags
Indianapolis Bus Station
Boston (South Station)
No tags
Next departures for Indianapolis to Boston on December 28
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Boston (South Station)
Cheapest
Downtown Transit Center
151 Steel Pl, Cambridge
Fastest
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
Boston (South Station)
No tags
Indianapolis Bus Station
Boston (South Station)
No tags
Downtown Transit Center
Brookline
No tags
Next departures for Indianapolis to Boston on December 29
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Boston (South Station)
Cheapest
Downtown Transit Center
151 Steel Pl, Cambridge
Fastest
Greyhound Amtrak Station
South Station (Train Terminal)
No tags
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
Boston (South Station)
No tags
Indianapolis Bus Station
Boston (South Station)
No tags
Next departures for Indianapolis to Boston on December 31
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Boston (South Station)
Cheapest
FlixBus + Greyhound Lines, Inc.
Downtown Transit Center
Boston (South Station)
Fastest
Greyhound Amtrak Station
South Station (Train Terminal)
No tags
Greyhound Lines, Inc. + FlixBus
Indianapolis Bus Station
Boston (South Station)
No tags
Indianapolis Bus Station
Boston (South Station)
No tags
Last refresh of the prices: Last Sunday at 11:18 AM EST.
Compare 2 ways to go from Indianapolis to Boston
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Boston. The journey takes about 1 day, 5 hours 25 minutes and with fares starting at just $111, it presents an excellent value for a comfortable ride.
Based on 5673 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $151
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
FlixBus Indianapolis Boston recent customer reviews
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Indianapolis to Boston, MA, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Indianapolis to Boston?
The cheapest bus tickets from Indianapolis to Boston start from $111. The average price for this route is around $186. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Indianapolis to Boston?
The average bus trip duration from Indianapolis to Boston is 1d 5h, covering a distance of 804 miles (1297 km). The quickest bus can get you there in 1d 1h and is operated by Greyhound.
Which bus companies service the Indianapolis to Boston route?
Several major bus companies operate on this route with 17 buses available per day, including services from Amtrak, FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from Indianapolis to Boston?
The earliest bus departs from Indianapolis to Boston at 12:15am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Indianapolis to Boston?
A bus trip from Indianapolis to Boston generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Indianapolis to Boston?
According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5654 reviews.
Which bus company has the best Wi-Fi from Indianapolis to Boston?
Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.
Which bus company has the most timely service from Indianapolis to Boston?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Indianapolis to Boston?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
12/22
$281
12/23
$256
Today
$256
12/25
$238
12/26
$197
12/27
$224
12/28
$197
12/29
$190
The cheapest trip from Indianapolis to Boston, MA, US was searched and found on Dec 29, 2025 with a price of $190
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Boston, MA, US, as early as possible.
You can expect to pay from $190 to $2,438 for a bus ticket from Indianapolis to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $190 which is on 2025-12-29.
Usually Amtrak, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Indianapolis to Boston, MA, US?
The bus is the cheapest travel choice for this destination