Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Harrisburg Bus Station | Springfield Flixbus stop | No tags | ||||
| Bus | Harrisburg Bus Station | Springfield Flixbus stop | No tags | ||||
| Bus | Harrisburg Bus Station | Springfield Flixbus stop | No tags | ||||
| Bus | Harrisburg Bus Station | Springfield Flixbus stop | No tags | ||||
| Bus | Harrisburg Bus Station | Springfield Flixbus stop | No tags |
Get from Harrisburg to Springfield
The journey takes about 1 day, 3 hours 45 minutes and with fares starting at just $135, it presents an excellent value for a comfortable ride.
Where are the popular stops in Harrisburg and Springfield?
Stops in Harrisburg
- A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101
Stops in Springfield
- A
Greyhound Station
2425 E Kearney St, Springfield, MO 65803 - B
I-44 & Kansas Expy
2825 N Kansas Expy, Springfield, MO 65806, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Harrisburg to Springfield, MO by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Harrisburg to Springfield?
The cheapest bus tickets from Harrisburg to Springfield start from $135. The average price for this route is around $232. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Harrisburg to Springfield?
The average bus trip duration from Harrisburg to Springfield is 1d 3h, covering a distance of 907 miles (1462 km). The quickest bus can get you there in 1d 3h and is operated by Greyhound.
Which bus companies service the Harrisburg to Springfield route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Harrisburg to Springfield?
The earliest bus departs from Harrisburg to Springfield at 2:30am. And the latest bus departs at 9:10pm.
What are the CO₂ emissions for the bus trip from Harrisburg to Springfield?
A bus trip from Harrisburg to Springfield generates an estimated 37 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to Springfield, MO was searched and found on Dec 25, 2025 with a price of $168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Springfield, MO, as early as possible.
You can expect to pay from $168 to $408 for a bus ticket from Harrisburg to Springfield, MO based on the last 2 days. You can expect to find the cheapest price for the trip at $219 which is on 2025-12-28.
