Bus Tickets from Fort Myers to Buffalo, NY

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TodayAug 24
TomorrowAug 25
TueAug 26
WedAug 27
from $151
ThuAug 28
FriAug 29
SatAug 30
SunAug 31

Next departures to Buffalo

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: August 27 at
    Departure city: Fort Myers
    Departure location: Fort Myers-Cape Coral
    Arrival time: August 29 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: August 27 at
    Departure city: Fort Myers
    Departure location: Love's Travel Stop
    Arrival time: August 29 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Fort Myers
    Departure location: Love's Travel Stop
    Arrival time: August 29 at
    Destination city: Buffalo
    Destination location: Depew Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Fort Myers
    Departure location: Fort Myers-Cape Coral
    Arrival time: August 29 at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: August 27 at
    Departure city: Fort Myers
    Departure location: Fort Myers-Cape Coral
    Arrival time: August 29 at
    Destination city: Buffalo
    Destination location: Buffalo (BUF) Airport
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Bus Fort Myers to Buffalo, NY: Trip Overview

Average ticket price$182
Average bus trip duration1d 19h
Number of daily buses6
Earliest bus departure12:20pm
Distance1138 miles (1834 km)
Latest bus departure6:35pm

Fort Myers to Buffalo Bus

With Busbud, comparing and booking tickets for a bus from Fort Myers to Buffalo is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Fort Myers to Buffalo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Fort Myers to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Fort Myers - Buffalo, NY

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/22
No data
08/23
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Today
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08/25
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08/26
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08/27
$1,202
08/28
No data
08/29
No data
busbud logoThe cheapest trip from Fort Myers to Buffalo, NY was searched and found on Aug 27, 2025 with a price of $1,202

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Fort Myers to Buffalo, NY, as early as possible.

You can expect to pay from $1,202 to $1,202 for a bus ticket from Fort Myers to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $1,202 which is on 2025-08-27.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Fort Myers to Buffalo.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Fort Myers to Buffalo, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Fort Myers to Buffalo will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Fort Myers to Buffalo while indulging in miles on end of beautiful scenic views.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to Fort Myers by bus?

Bus from Buffalo, NY to Fort Myers

You can also go to Buffalo, NY by train

Train from Fort Myers to Buffalo, NY

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