- Florence to St. Louis buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Florence, SC | Gateway Station | No tags | ||||
Greyhound + FlixBus | Bus | Florence, SC | St Louis, MO | No tags | ||||
FlixBus + Greyhound | Bus | Florence, SC | Gateway Station | No tags | ||||
Greyhound + FlixBus | Bus | Florence, SC | Gateway Station | No tags | ||||
FlixBus + Greyhound | Bus | Florence, SC | Gateway Station | No tags |
Compare 2 ways to go from Florence to St. Louis
Among the sustainable travel choices, the Bus stands out as a good way to reach St. Louis. The journey takes about 1 day, 4 hours 25 minutes and with fares starting at just $174, it presents an excellent value for a comfortable ride.
Where are the popular stops in Florence and St. Louis?
Stops in Florence
- A619 S Irby St, Florence, SC 29501, USA
- B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Florence, SC, US to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Florence to St. Louis?
The cheapest bus tickets from Florence to St. Louis start from $174. The average price for this route is around $174. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to St. Louis?
The average bus trip duration from Florence to St. Louis is 1d 4h, covering a distance of 655 miles (1056 km). The quickest bus can get you there in 1d and is operated by Greyhound.
Which bus companies service the Florence to St. Louis route?
Several major bus companies operate on this route with 3 buses available per day.
What is the earliest and latest departure time for the bus from Florence to St. Louis?
The earliest bus departs from Florence to St. Louis at 12:05am. And the latest bus departs at 4:10pm.
What are the CO₂ emissions for the bus trip from Florence to St. Louis?
A bus trip from Florence to St. Louis generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.






