How much is the bus ticket from Florence to Indianapolis?

The cheapest bus tickets from Florence to Indianapolis start from $105. The average price for this route is around $106. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Florence to Indianapolis?

The average bus trip duration from Florence to Indianapolis is 20h 30m, covering a distance of 521 miles (841 km). The quickest bus can get you there in 19h 55m and is operated by Greyhound .

Which bus companies service the Florence to Indianapolis route?

Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Florence to Indianapolis?

The earliest bus departs from Florence to Indianapolis at 12:05am. And the latest bus departs at 4:10pm.

What are the CO₂ emissions for the bus trip from Florence to Indianapolis?

A bus trip from Florence to Indianapolis generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Florence to Indianapolis?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87435 reviews.

Which bus company has the best Wi-Fi from Florence to Indianapolis?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Florence to Indianapolis?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Florence to Indianapolis?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Florence to Indianapolis from $97 | Refundable Tickets

Previously seen trips

Next departures for Florence to Indianapolis on December 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound + FlixBus	Bus	5:35am	Florence, SC	1d 2h	8:00am	Downtown Transit Center	No tags
FlixBus + Greyhound	Bus	5:35am	Florence, SC	1d 4h	10:15am	Indianapolis Bus Station	No tags
Greyhound + FlixBus	Bus	5:35am	Florence, SC	1d 4h	10:15am	Indianapolis Bus Station	No tags
	Bus	11:59pm	Florence, SC	1d 8h	8:00am	Downtown Transit Center	No tags
FlixBus + Greyhound	Bus	11:59pm	Florence, SC	1d 4h	4:55am	Indianapolis Bus Station	No tags

Compare 2 ways to go from Florence to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 20 hours 30 minutes and with fares starting at just $105, it presents an excellent value for a comfortable ride.

4bus per day

20h 30mAverage Duration

521 milesDistance

21kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$105 - $150	Average Duration20h 30m	CO₂ emissions 21kg CO₂e
Train	Average Price$275 - $275	Average Duration1d 5h	CO₂ emissions 76kg CO₂e

Where are the popular stops in Florence and Indianapolis?

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/587,456 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/511,768 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Florence, SC, US to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Florence to Indianapolis?
The cheapest bus tickets from Florence to Indianapolis start from $105. The average price for this route is around $106. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Florence to Indianapolis?
The average bus trip duration from Florence to Indianapolis is 20h 30m, covering a distance of 521 miles (841 km). The quickest bus can get you there in 19h 55m and is operated by Greyhound.
Which bus companies service the Florence to Indianapolis route?
Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Florence to Indianapolis?
The earliest bus departs from Florence to Indianapolis at 12:05am. And the latest bus departs at 4:10pm.
What are the CO₂ emissions for the bus trip from Florence to Indianapolis?
A bus trip from Florence to Indianapolis generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Florence to Indianapolis?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.
Which bus company has the best Wi-Fi from Florence to Indianapolis?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Florence to Indianapolis?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Florence to Indianapolis?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.