Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Detroit Bus Station | Opelika (4th Street Station) | CheapestFastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Detroit Bus Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Detroit Bus Station | Opelika (4th Street Station) | No tags | ||||
| Bus | Detroit Bus Station | Opelika (4th Street Station) | No tags |
Last refresh of the prices: Last Wednesday at 4:50 AM EST.
Get from Detroit to Opelika
The journey takes about 1 day, 2 hours 25 minutes and with fares starting at just $133, it presents an excellent value for a comfortable ride.
Where are the popular stops in Detroit and Opelika?
Stops in Opelika
- A
McDonald's - Opelika
1104 Columbus Pkwy, Opelika, AL 36801, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Detroit, MI to Opelika by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Detroit to Opelika?
The cheapest bus tickets from Detroit to Opelika start from $133. The average price for this route is around $177. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Detroit to Opelika?
The average bus trip duration from Detroit to Opelika is 1d 2h, covering a distance of 680 miles (1096 km). The quickest bus can get you there in 21h 35m and is operated by Greyhound.
Which bus companies service the Detroit to Opelika route?
Several major bus companies operate on this route with 4 buses available per day.
What is the earliest and latest departure time for the bus from Detroit to Opelika?
The earliest bus departs from Detroit to Opelika at 7:15am. And the latest bus departs at 11:25pm.
What are the CO₂ emissions for the bus trip from Detroit to Opelika?
A bus trip from Detroit to Opelika generates an estimated 27 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Detroit, MI to Opelika was searched and found on Feb 2, 2026 with a price of $121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Detroit, MI to Opelika, as early as possible.
You can expect to pay from $121 to $193 for a bus ticket from Detroit, MI to Opelika based on the last 2 days. You can expect to find the cheapest price for the trip at $121 which is on 2026-02-02.
