Bus Tickets from Des Moines to Springfield, MO

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Previously seen trips

One passenger / one way

  • Departure time: November 8 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: November 9 at
    Destination city: Springfield
    Destination location: Springfield Flixbus stop
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: November 23 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: November 24 at
    Destination city: Springfield
    Destination location: Springfield Flixbus stop
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: January 12 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: January 13 at
    Destination city: Springfield
    Destination location: Springfield Flixbus stop
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: Des Moines
    Departure location: Des Moines
    Arrival time: May 15 at
    Destination city: Springfield
    Destination location: 255 North Grant Avenue
    Operated by: Jefferson LinesJefferson Lines
    Vehicle: BusDuration:
  • Departure time: May 15 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: May 16 at
    Destination city: Springfield
    Destination location: Springfield Flixbus stop
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Des Moines to Springfield, MO: Trip Overview

Average ticket price$132
Average bus trip duration13h 10m
Number of daily buses1
Earliest bus departure4:20am
Distance306 miles (492 km)
Latest bus departure11:45pm

Des Moines to Springfield Bus

Busbud helps you find a bus from Des Moines to Springfield. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Des Moines to Springfield from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from Des Moines to Springfield, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Des Moines - Springfield, MO

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/26
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08/27
$128
Today
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08/29
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08/30
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08/31
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busbud logoThe cheapest trip from Des Moines to Springfield, MO was searched and found on Aug 27, 2025 with a price of $128

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Springfield, MO, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Springfield!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Des Moines to Springfield, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Springfield that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Des Moines to Springfield while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Des Moines by bus?

Bus from Springfield, MO to Des Moines

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