Bus Tickets from Denver to Knoxville, TN

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Previously seen trips

One passenger / one way

  • Departure time: September 16 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: September 18 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: September 16 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: September 18 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: October 1 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: October 3 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: October 26 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: October 28 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: October 26 at
    Departure city: Denver
    Departure location: DENVER
    Arrival time: October 28 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Denver to Knoxville, TN: Trip Overview

Average ticket price$170
Average bus trip duration1d 20h
Number of daily buses3
Earliest bus departure7:50am
Distance1176 miles (1896 km)
Latest bus departure8:10pm

Denver to Knoxville Bus

With Busbud, comparing and booking tickets for a bus from Denver to Knoxville is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Denver to Knoxville.

Discover how much the bus trip from Denver to Knoxville will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Denver - Knoxville, TN

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/30
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$233
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busbud logoThe cheapest trip from Denver to Knoxville, TN was searched and found on Sep 1, 2025 with a price of $233

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to Knoxville, TN, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Denver to Knoxville.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Denver to Knoxville.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Denver to Knoxville will emit less CO2 than a car or an airplane.

Make a music playlist for your bus ride from Denver to Knoxville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travelers have used their electronic device on board during 2014.

Will you be returning to Denver by bus?

Bus from Knoxville, TN to Denver

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