Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound | Bus | Clarksville Park&Ride | 4565 Gaynor Ave, North Charleston | No tags | ||||
Greyhound + FlixBus | Bus | Clarksville Park&Ride | 4565 Gaynor Ave, North Charleston | No tags | ||||
 | Bus | Clarksville Park&Ride | 4565 Gaynor Ave, North Charleston | No tags | ||||
| Bus | Clarksville Park&Ride | 4565 Gaynor Ave, North Charleston | No tags | ||||
| Bus | Clarksville Park&Ride | 4565 Gaynor Ave, North Charleston | No tags |
Get from Clarksville to Charleston
The journey takes about 21 hours 15 minutes and with fares starting at just $96, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Clarksville, TN to Charleston, SC, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Clarksville to Charleston?
The cheapest bus tickets from Clarksville to Charleston start from $96. The average price for this route is around $117. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Clarksville to Charleston?
The average bus trip duration from Clarksville to Charleston is 21h 15m, covering a distance of 481 miles (775 km). The quickest bus can get you there in 21h 15m and is operated by Greyhound.
Which bus companies service the Clarksville to Charleston route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Clarksville to Charleston?
The earliest bus departs from Clarksville to Charleston at 8:15pm. And the latest bus departs at 8:15pm.
What are the CO₂ emissions for the bus trip from Clarksville to Charleston?
A bus trip from Clarksville to Charleston generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Clarksville, TN to Charleston, SC, US was searched and found on Jan 25, 2026 with a price of $89To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Clarksville, TN to Charleston, SC, US, as early as possible.
You can expect to pay from $89 to $110 for a bus ticket from Clarksville, TN to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $89 which is on 2026-01-25.
