Bus from Cincinnati to San Diego, CA, US: Tickets & Schedules

Next bus departures

Next departures for Cincinnati to San Diego on December 29
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Cincinnati Bus Station
Downtown SD (Seaport)Cheapest
Greyhound Lines, Inc. + FlixBus
Bus
Cincinnati Bus Station
UCSD Health La Jolla StationFastest
Greyhound Lines, Inc. + FlixBus
Bus
Cincinnati Bus Station
San Diego (Old Town-FlixBus)No tags
Greyhound Lines, Inc.Bus
Cincinnati Bus Station
Greyhound Bus StopNo tags

Last refresh of the prices: Yesterday at 6:24 PM EST.

Compare 2 ways to go from Cincinnati to San Diego

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach San Diego. The journey takes about 2 days, 11 hours 45 minutes and with fares starting at just $464, it presents an excellent value for a comfortable ride.

14bus per day
2d 11hAverage Duration
1869 milesDistance
75kgCO₂ emissions
Average Price$464 - $601Average Duration2d 11h
75kg CO₂e
Average Price$575 - $576Average Duration2d 14h
274kg CO₂e

Frequently asked questions about traveling from Cincinnati to San Diego, CA, US by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Cincinnati to San Diego?

    The cheapest bus tickets from Cincinnati to San Diego start from $464. The average price for this route is around $573. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Cincinnati to San Diego?

    The average bus trip duration from Cincinnati to San Diego is 2d 11h, covering a distance of 1869 miles (3014 km). The quickest bus can get you there in 2d 3h and is operated by Greyhound.

  3. Which bus companies service the Cincinnati to San Diego route?

    Several major bus companies operate on this route with 14 buses available per day, including services from Greyhound, FlixBus.

  4. What is the earliest and latest departure time for the bus from Cincinnati to San Diego?

    The earliest bus departs from Cincinnati to San Diego at 12:55am. And the latest bus departs at 5:00pm.

  5. What are the CO₂ emissions for the bus trip from Cincinnati to San Diego?

    A bus trip from Cincinnati to San Diego generates an estimated 75 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Cincinnati to San Diego?

    According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87435 reviews.

  7. Which bus company has the best Wi-Fi from Cincinnati to San Diego?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from Cincinnati to San Diego?

    According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Cincinnati to San Diego?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/27
No data
12/28
$391
Today
$498
12/30
No data
12/31
No data
busbud logoThe cheapest trip from Cincinnati to San Diego, CA, US was searched and found on Dec 28, 2025 with a price of $391

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to San Diego, CA, US, as early as possible.

What's the cheapest way to go from Cincinnati to San Diego, CA, US?

busbud logoThe bus is the cheapest travel choice for this destination

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