How can I travel from Chicago to Jefferson City without flying?

Both buses and trains are available for traveling between these two cities. The two options are convenient and sustainable ways to reach Jefferson City. Another option you should consider is using carpooling services, which allow you to share a car ride with other travelers.

How long does it take to get to Jefferson City from Chicago by bus?

Traveling from Chicago to Jefferson City takes about 18h 45m on average, but the quickest bus can get you there in about 18h 15m. This is the time it takes to travel the 329 miles (531 km) that separate the two cities.

What is the travel distance from Chicago to Jefferson City?

Chicago and Jefferson City are 329 miles (531 km) apart.

What is the most affordable way to travel from Chicago to Jefferson City?

If you want the cheapest way to travel this route, take the bus. The lowest price for the bus on this route is $45.

How much are the bus tickets from Chicago to Jefferson City?

The bus ticket costs $93 on average. In the past 30 days, prices have fluctuated between $45 and $187, so it's best to compare them to make sure you get the best deal.

Is there an overnight bus from Chicago to Jefferson City?

Yes, it is possible to take an overnight bus from Chicago to Jefferson City. Remember to bring along essentials like a blanket and some snacks to ensure a cozy and convenient journey.

Bus Chicago to Jefferson City (MO) from $50 | Compare & Save up to 60%

TodayJun 14

from $97

TomorrowJun 15

from $138

MonJun 16

from $146

TueJun 17

from $126

WedJun 18

from $88

ThuJun 19

from $58

FriJun 20

from $105

SatJun 21

Cheap buses leaving tomorrow

One passenger / one way

This trip is recommended because it is: Cheapest
Departure time: June 15 at 9:45pm
Departure city: Chicago
Departure location: Downtown Greyhound Station
Arrival time: June 16 at 4:45pm
Destination city: Jefferson City
Destination location: Jefferson City
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 19h
This trip is recommended because it is: Fastest
Departure time: June 15 at 10:30pm
Departure city: Chicago
Departure location: Chicago 95Th & Dan Ryan
Arrival time: June 16 at 4:45pm
Destination city: Jefferson City
Destination location: Jefferson City
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 18h 15m
Departure time: June 15 at 10:00pm
Departure city: Chicago
Departure location: 537-517 W. Jackson Blvd
Arrival time: June 16 at 4:45pm
Destination city: Jefferson City
Destination location: Jefferson City
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 18h 45m
Departure time: June 15 at 10:30pm
Departure city: Chicago
Departure location: Chicago 95Th & Dan Ryan
Arrival time: June 16 at 4:45pm
Destination city: Jefferson City
Destination location: Jefferson City
Operated by: Greyhound Lines, Inc.
Vehicle: BusDuration: 18h 15m

Accepted payments

Compare 2 ways to go from Chicago to Jefferson City.

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$45 - $187	Average Duration18h 45m	CO₂ emissions 13kg CO₂e5 out of 5 stars	CheapestMost eco-friendly
Train	Average Price$49 - $141	Average Duration7h 46m	CO₂ emissions 48kg CO₂e1 out of 5 stars	Fastest

Busbud recommends taking the train from Chicago to Jefferson City

Among the sustainable travel choices, the train stands out as the good way to reach Jefferson City. The journey takes about 7 hours 46 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.

2train per day

7h 46mAverage Duration

$49Cheapest ticket

48kgCO₂ emissions

Bus Chicago to Jefferson City: Trip Overview

Average ticket price$93

Average bus trip duration18h 45m

Number of daily buses3

Earliest bus departure9:45pm

Distance324 miles (522 km)

Latest bus departure10:30pm

Compare bus companies

Greyhound

3.5/587,032 reviews

Staff3.6

Timeliness2.8

Cleanliness3.3

Wifi2.3

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/59,043 reviews

Staff4.1

Timeliness4

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies: FlixBus, Greyhound, Tornado Bus, Los Limousines, Valley Transit, Tufesa, Wanda Coach

Chicago to Jefferson City Bus

With Busbud, comparing and booking tickets for a bus from Chicago to Jefferson City is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make it our job to connect you with the most dependable bus companies that cover bus service from Chicago to Jefferson City.

Discover how much the bus trip from Chicago to Jefferson City will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions for your trip Chicago - Jefferson City (MO)

How can I travel from Chicago to Jefferson City without flying?
How long does it take to get to Jefferson City from Chicago by bus?
What is the travel distance from Chicago to Jefferson City?
What is the most affordable way to travel from Chicago to Jefferson City?
How much are the bus tickets from Chicago to Jefferson City?
Is there an overnight bus from Chicago to Jefferson City?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

06/12

$109

06/13

$124

Today

$89

06/15

$131

06/16

$138

06/17

$119

06/18

$81

06/19

$50

The cheapest trip from Chicago to Jefferson City was searched and found on Jun 19, 2025 with a price of $50

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Jefferson City, as early as possible.

You can expect to pay from $50 to $266 for a bus ticket from Chicago to Jefferson City based on the last 2 days. You can expect to find the cheapest price for the trip at $50 which is on 2025-06-19.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Chicago to Jefferson City.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Chicago to Jefferson City.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Chicago to Jefferson City will emit less CO2 than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Chicago to Jefferson City.

Did you know?

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to Chicago by bus?

Bus from Chicago to Jefferson City

You can also go to Jefferson City by train

Train from Chicago to Jefferson City

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

Bus Tickets from Chicago to Jefferson City (MO)

One passenger / one way

Cheap buses leaving tomorrow

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

One passenger / one way

Compare 2 ways to go from Chicago to Jefferson City.

Bus Chicago to Jefferson City: Trip Overview

Compare bus companies

Chicago to Jefferson City Bus

Frequently asked questions for your trip Chicago - Jefferson City (MO)

How can I travel from Chicago to Jefferson City without flying?

How long does it take to get to Jefferson City from Chicago by bus?

What is the travel distance from Chicago to Jefferson City?

What is the most affordable way to travel from Chicago to Jefferson City?

How much are the bus tickets from Chicago to Jefferson City?

Is there an overnight bus from Chicago to Jefferson City?

Find cheapest prices for buses

About Bus Travel

Bus Travel Tips

Did you know?

Will you be returning to Chicago by bus?

You can also go to Jefferson City by train

Top traveled bus routes

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

People from around the world trust Busbud

Popular Buses Connecting Chicago

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Buses Leaving from Jefferson City

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