Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Niagara Frontier Transportation Authority | Jacksonville Bus Station | CheapestFastest | ||||
| Bus | Buffalo (BUF) Airport | Jacksonville Bus Station | No tags |
Last refresh of the prices: Yesterday at 3:37 PM EST.
Compare 2 ways to go from Buffalo to Jacksonville
Among the sustainable travel choices, the train stands out as the good way to reach Jacksonville. The journey takes about 1 day, 4 hours 39 minutes and with fares starting at just $225, it presents an excellent value for a comfortable ride.
Where are the popular stops in Buffalo and Jacksonville?
Stops in Buffalo
- B185 Ellicott St, Buffalo, NY 14203, USA
- C75 Exchange St, Buffalo, NY 14203, USA
Stops in Jacksonville
- A
W Forsyth St
1111 W Forsyth St, Jacksonville, FL 32204, USA - B3570 Clifford Ln, Jacksonville, FL 32209, USA
- C
Kings Avenue Station
1003 Kings Avenue, Jacksonville, FL 32207 - D
JRTC Greyhound Bus Station
111 W. Forsyth St, Jacksonville, FL 32202, USA
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Buffalo, NY to Jacksonville, FL by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Buffalo to Jacksonville?
The cheapest bus tickets from Buffalo to Jacksonville start from $149. The average price for this route is around $291. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Buffalo to Jacksonville?
The average bus trip duration from Buffalo to Jacksonville is 1d 10h, covering a distance of 884 miles (1426 km). The quickest bus can get you there in 1d 11h and is operated by FlixBus.
Which bus companies service the Buffalo to Jacksonville route?
Several major train operators operate on this route with 4 trains available per day.
What is the earliest and latest departure time for the bus from Buffalo to Jacksonville?
The earliest bus departs from Buffalo to Jacksonville at 12:55am. And the latest bus departs at 11:59pm.
What are the CO₂ emissions for the bus trip from Buffalo to Jacksonville?
A bus trip from Buffalo to Jacksonville generates an estimated 36 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Jacksonville, FL was searched and found on Dec 29, 2025 with a price of $189To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Buffalo, NY to Jacksonville, FL, as early as possible.
You can expect to pay from $189 to $340 for a bus ticket from Buffalo, NY to Jacksonville, FL based on the last 2 days. You can expect to find the cheapest price for the trip at $189 which is on 2025-12-29.
