Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | BP Station I-85 & SC-81 | Gateway Station | CheapestFastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | BP Station I-85 & SC-81 | Gateway Station | No tags |
Last refresh of the prices: Last Saturday at 11:32 AM EST.
Get from Anderson to St. Louis
The journey takes about 15 hours 35 minutes and with fares starting at just $141, it presents an excellent value for a comfortable ride.
Where are the popular stops in Anderson and St. Louis?
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Anderson, SC to St. Louis by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Anderson to St. Louis?
The cheapest bus tickets from Anderson to St. Louis start from $141. The average price for this route is around $143. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Anderson to St. Louis?
The average bus trip duration from Anderson to St. Louis is 15h 35m, covering a distance of 503 miles (811 km). The quickest bus can get you there in 15h 35m and is operated by Greyhound.
Which bus companies service the Anderson to St. Louis route?
Several major train operators operate on this route with 3 trains available per day.
What is the earliest and latest departure time for the bus from Anderson to St. Louis?
The earliest bus departs from Anderson to St. Louis at 1:20am. And the latest bus departs at 10:20pm.
What are the CO₂ emissions for the bus trip from Anderson to St. Louis?
A bus trip from Anderson to St. Louis generates an estimated 20 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Anderson, SC to St. Louis was searched and found on Dec 28, 2025 with a price of $151To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Anderson, SC to St. Louis, as early as possible.
