Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | Panama City Beach Station | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | Panama City Beach Station | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | Panama City Beach Station | No tags |
Get from Tupelo to Panama City
The journey takes about 1 day, 1 hour 40 minutes, and with fares starting at just R 2 721, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 721
Frequently asked questions about travelling from Tupelo to Panama City, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Tupelo to Panama City?
The cheapest bus tickets from Tupelo to Panama City start at R 2 721. The average price for this route is around R 2 721. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Tupelo to Panama City?
The average bus journey time from Tupelo to Panama City is 1d 1h, covering a distance of 527 km. The fastest bus gets you there in 1d 1h and is operated by Greyhound.
Which bus companies service the Tupelo to Panama City route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Tupelo to Panama City?
The earliest bus departs from Tupelo to Panama City at 10:55. And the latest bus departs at 10:55.
What are the CO₂ emissions for the bus trip from Tupelo to Panama City?
A bus trip from Tupelo to Panama City produces an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Panama City, US was searched and found on 07 Jan 2026 with a price of R 2 304To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Panama City, US as early as possible.
