Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | Panama City Beach Station | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | Panama City Beach Station | No tags | ||||
| Bus | Tupelo (Brothers Quick Stop) | Panama City Beach Station | No tags |
Get from Tupelo to Panama City
The journey takes about 1 day, 1 hour 40 minutes, and with fares starting at just $229, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $229
Frequently asked questions about travelling from Tupelo to Panama City, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to Panama City?
The cheapest bus tickets from Tupelo to Panama City start from $229. The average price for this route is around $229. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to Panama City?
The average bus travel time from Tupelo to Panama City is 1d 1h, covering a distance of 527 km. The quickest bus can get you there in 1d 1h and is operated by Greyhound.
Which bus companies service the Tupelo to Panama City route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Tupelo to Panama City?
The earliest bus departs from Tupelo to Panama City at 10:55am. And the latest bus departs at 10:55am.
What are the CO₂ emissions for the bus trip from Tupelo to Panama City?
A bus trip from Tupelo to Panama City generates an estimated 13 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Panama City, US was searched and found on Jan 7, 2026 with a price of $194To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Panama City, US, as early as possible.
