Next departures from Mexicali to Santa Ana on 31 January
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Cheapest
Bus
Mexicali - Stop
Santa Ana (Paso) - Stop
Fastest
Bus
Tufesa
Santa Ana Col Del Rio
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Next departures from Mexicali to Santa Ana on 1 February
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Cheapest
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Fastest
Bus
Mexicali - Stop
Santa Ana (Paso) - Stop
No tags
Bus
Tufesa
Santa Ana Col Del Rio
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Next departures from Mexicali to Santa Ana on 2 February
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Cheapest
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Fastest
Bus
Mexicali - Stop
Santa Ana (Paso) - Stop
No tags
Bus
Tufesa
Santa Ana Col Del Rio
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Next departures from Mexicali to Santa Ana on 3 February
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Cheapest
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Fastest
Bus
Mexicali - Stop
Santa Ana (Paso) - Stop
No tags
Bus
Tufesa
Santa Ana Col Del Rio
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Next departures from Mexicali to Santa Ana on 4 February
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
CheapestFastest
Bus
Mexicali - Stop
Santa Ana (Paso) - Stop
No tags
Bus
Tufesa
Santa Ana Col Del Rio
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Next departures from Mexicali to Santa Ana on 5 February
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Cheapest
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Fastest
Bus
Mexicali - Stop
Santa Ana (Paso) - Stop
No tags
Bus
Tufesa
Santa Ana Col Del Rio
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Next departures from Mexicali to Santa Ana on 6 February
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Cheapest
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
Fastest
Bus
Mexicali - Stop
Santa Ana (Paso) - Stop
No tags
Bus
Tufesa
Santa Ana Col Del Rio
No tags
Bus
Mexicali Central Bus Station, Avenida Francisco Sarabia 1298, Mexicali
Santa Ana
No tags
Last refresh of the prices: Last Thursday at 3:13 AM PST.
Compare 2 ways to travel from Mexicali to Santa Ana
We recommend taking the bus
Among the sustainable travel choices, the Bus stands out as a good way to reach Santa Ana. The journey takes about 7 hours 10 minutes and with fares starting at just R 854, it presents an excellent value for a comfortable ride.
Based on 707 reviews, the company was rated 3.4 stars on Busbud. Travellers were especially satisfied with the seats and the temperature but often complained about the timeliness. Tufesa ticket prices on this trip start at R 1 026
Based on 167 reviews, the company was rated 3.1 stars on Busbud. Travellers were especially satisfied with the ticket access and the seats but often complained about the Wi-Fi. Chihuahuenses ticket prices on this trip start at R 889
Based on 4 reviews, the company was rated 4 stars on Busbud. Travellers were especially satisfied with the departure location and the timeliness but often complained about the seats. Interbus de Sinaloa ticket prices on this trip start at R 1 045
Aguacaliente offers 3 daily departures, and you can find tickets starting at R 854. The quickest ride takes around 441. Aguacaliente offers a cost-effective solution to get you where you need to be.
Based on 763 reviews, the company was rated 3.4 stars on Busbud. Travellers were especially satisfied with the seats and the departure location but often complained about the Wi-Fi. Futura ticket prices on this trip start at R 889
Frequently asked questions about travelling from Mexicali to Santa Ana, SON, MX by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Mexicali to Santa Ana?
The cheapest bus tickets from Mexicali to Santa Ana start at R 854. The average price for this route is around R 910. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Mexicali to Santa Ana?
The average bus journey time from Mexicali to Santa Ana is 7h 10m, covering a distance of 473 km. The fastest bus gets you there in 5h 30m and is operated by Interbus de Sinaloa.
Which bus companies service the Mexicali to Santa Ana route?
What is the earliest and latest departure time for the bus from Mexicali to Santa Ana?
The earliest bus departs from Mexicali to Santa Ana at 00:15. And the latest bus departs at 23:59.
What are the CO₂ emissions for the bus trip from Mexicali to Santa Ana?
A bus trip from Mexicali to Santa Ana produces an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
What is the best bus company from Mexicali to Santa Ana?
According to Busbud customers, the highest-rated bus company on this route is Interbus de Sinaloa, with an average rating of 4.0 out of 5 stars based on 4 reviews.
Which bus company has the best Wi-Fi from Mexicali to Santa Ana?
Based on reviews on Busbud, the bus company Tufesa has the best Wi-Fi rating with a score of 3.0.
Which bus company offers the most punctual service from Mexicali to Santa Ana?
According to Busbud traveller reviews, the most punctual bus company on this route is Interbus de Sinaloa, with a punctuality rating of 3.4 out of 5 stars.
Which bus company has the cleanest buses from Mexicali to Santa Ana?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tufesa, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
29/01
R 861
30/01
R 859
Today
R 866
01/02
R 866
02/02
R 850
03/02
R 928
04/02
R 917
05/02
R 850
The cheapest trip from Mexicali to Santa Ana, SON, MX was searched and found on 02 Feb 2026 with a price of R 850
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Santa Ana, SON, MX as early as possible.
You can expect to pay from R 850 to R 1 097 for a bus ticket from Mexicali to Santa Ana, SON, MX based on the last 2 days. You can expect to find the cheapest price for the trip at R 850, which is on 2026-02-02.
Usually Tufesa will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.