Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Des Moines | 151 Steel Pl, Cambridge | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Des Moines | Boston (South Station) | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Des Moines | Brookline | No tags |
Last refresh of the prices: Yesterday at 12:58 PM CST.
Get from Des Moines to Boston
The journey takes about 1 day, 19 hours 10 minutes, and with fares starting at just R 2 274, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Boston?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C335 Grove St, Auburndale, MA 02466
- D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at R 2 418
Frequently asked questions about travelling from Des Moines to Boston, MA, US by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Des Moines to Boston?
The cheapest bus tickets from Des Moines to Boston start at R 2 274. The average price for this route is around R 4 037. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Des Moines to Boston?
The average bus journey time from Des Moines to Boston is 1d 19h, covering a distance of 1854 km. The fastest bus gets you there in 1d 11h and is operated by Greyhound.
Which bus companies service the Des Moines to Boston route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Des Moines to Boston?
The earliest bus departs from Des Moines to Boston at 09:25. And the latest bus departs at 09:30.
What are the CO₂ emissions for the bus trip from Des Moines to Boston?
A bus trip from Des Moines to Boston produces an estimated 46 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Boston, MA, US was searched and found on 07 Jan 2026 with a price of R 3 661To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Boston, MA, US as early as possible.
