Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | San Ysidro Bus terminal | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Boston (South Station) | San Ysidro Bus terminal | Fastest | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Brookline | San Ysidro Bus terminal | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | 151 Steel Pl, Cambridge | San Ysidro Bus terminal | No tags |
Last refresh of the prices: Today at 1:04 AM EST.
Get from Boston to San Ysidro
The journey takes about 3 days, 13 hours 50 minutes, and with fares starting at just R 3 669, it presents an excellent value for a comfortable ride.
Where are the popular stops in Boston and San Ysidro?
Stops in Boston
- A145 Dartmouth St, Boston, MA 02116, USA
- B100 Legends Way, Boston, MA 02114, USA
- C335 Grove St, Auburndale, MA 02466
- D
Prudential MBTA Station
220 Huntington Ave, Boston, MA 02115, USA - E
Copley MBTA Station
650 Boylston St, Boston, MA 02116, USA - F
Long Wharf
66 Long Wharf, Boston, MA 02110, USA
Compare bus companies
Based on 87518 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained about the Wi-Fi. Greyhound ticket prices on this trip start at R 3 718
Frequently asked questions about travelling from Boston, MA, US to San Ysidro, CA by bus
Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.
How much is the bus ticket from Boston to San Ysidro?
The cheapest bus tickets from Boston to San Ysidro start at R 3 669. The average price for this route is around R 3 758. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the bus journey from Boston to San Ysidro?
The average bus journey time from Boston to San Ysidro is 3d 13h, covering a distance of 4144 km. The fastest bus gets you there in 3d 1h and is operated by Greyhound.
Which bus companies service the Boston to San Ysidro route?
Several major bus companies operate on this route with 5 buses available per day.
What is the earliest and latest departure time for the bus from Boston to San Ysidro?
The earliest bus departs from Boston to San Ysidro at 01:30. And the latest bus departs at 20:55.
What are the CO₂ emissions for the bus trip from Boston to San Ysidro?
A bus trip from Boston to San Ysidro produces an estimated 104 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to San Ysidro, CA was searched and found on 30 Jan 2026 with a price of R 4 945To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Boston, MA, US to San Ysidro, CA as early as possible.
