Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | South Station (Train Terminal) | Greenville Station | Cheapest | ||||
Amtrak Acela + Amtrak | Train | Boston Route 128, MA | Greenville Station | Fastest | ||||
| Train | South Station (Train Terminal) | Greenville Station | No tags | ||||
Amtrak Acela + Amtrak | Train | South Station (Train Terminal) | Greenville Station | No tags | ||||
| Train | South Station (Train Terminal) | Greenville Station | No tags |
Last refresh of the prices: Last Monday at 21:51 EST.
Compare 2 ways to travel from Boston to Greenville
Among the sustainable travel choices, the Train stands out as a good way to reach Greenville. The journey takes about 20 hours 39 minutes and with fares starting at just £151, it presents an excellent value for a comfortable ride.
Train Companies
Frequently asked questions about travelling from Boston, MA, US to Greenville, SC by train
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much does a train ticket cost from Boston to Greenville?
The cheapest train tickets from Boston to Greenville start from £151. The average price for this train route is around £266. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.
How long is the train journey from Boston to Greenville?
The average train journey time from Boston to Greenville is 20h 39m, covering a distance of 799 miles. The fastest train gets you there in 19h 59m and is operated by Amtrak Acela.
Which train operators serve the Boston to Greenville route?
Several major train operators run on this route with 4 trains available per day, including services from Amtrak, Amtrak Acela.
What are the earliest and latest departure times for the train from Boston to Greenville?
The earliest train from Boston to Greenville departs at 08:12. And the latest train departs at 09:25.
Which is the best train operator from Boston to Greenville?
According to Busbud customers, the highest-rated train operator on this route is Amtrak Acela, with an average rating of 4.5 out of 5 stars based on 14 reviews.
Which train operator has the best Wi-Fi from Boston to Greenville?
According to reviews on Busbud, the train operator Amtrak Acela has the highest Wi-Fi rating with a score of 4.0.
Which train operator has the most punctual service from Boston to Greenville?
According to Busbud traveller reviews, the most punctual train operator on this route is Amtrak Acela, with a punctuality rating of 4.6 out of 5 stars.
Which train operator has the cleanest trains from Boston to Greenville?
According to Busbud traveller reviews, the train operator with the cleanest trains on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Boston, MA, US to Greenville, SC was searched and found on 8 Jan 2026 with a price of £170To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Boston, MA, US to Greenville, SC as early as possible.
You can expect to pay from £170 to £664 for a train ticket from Boston, MA, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at £184, which is on 2026-01-12.
