Find coaches from Milano to Palermo

Find affordable coach tickets from Milano to Palermo with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Today26 Jul
from US$207
Tomorrow27 Jul
from US$110
Mon28 Jul
from US$117
Tue29 Jul
from US$117
Wed30 Jul
from US$117
Thu31 Jul
from US$117
Fri1 Aug
from US$132
Sat2 Aug
from US$127

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 27 July at
    Departure city: Milano
    Departure location: Aeroporto Linate Airport (LIN)
    Arrival time: 28 July at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 27 July at
    Departure city: Milano
    Departure location: Milan San Donato Bus Station
    Arrival time: 28 July at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: 27 July at
    Departure city: Milano
    Departure location: Lampugnano
    Arrival time: 28 July at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:
  • Departure time: 27 July at
    Departure city: Milano
    Departure location: Lampugnano bus station
    Arrival time: 28 July at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Flixbus Flixbus
    Vehicle: BusDuration:
  • Departure time: 27 July at
    Departure city: Milano
    Departure location: Milan San Donato Bus Station
    Arrival time: 28 July at
    Destination city: Palermo
    Destination location: Terminal Bus Palermo
    Operated by: Autoservizi SalemiAutoservizi Salemi
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Milano to Palermo

Bus
Average priceUS$52 - US$257Average duration1d 1h
22kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average priceUS$71 - US$145Average duration16h 40m
37kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Milano to Palermo

Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 16 hours 40 minutes and with fares starting at just US$71, it presents an excellent value for a comfortable ride.

1carpool per day
16h 40mAverage duration
US$71Cheapest ticket
37kgCO₂ emissions

Bus Milano to Palermo: Trip Overview

Average ticket priceUS$128
Average bus trip duration1d 1h
Number of daily buses16
Earliest bus departure00:30
Distance547 miles
Latest bus departure23:50

Milano to Palermo Bus

Busbud helps you find a bus from Milano to Palermo. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Milano to Palermo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Milano to Palermo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Milano - Palermo

  1. How far is Palermo from Milano by coach?

    The distance between Milano and Palermo by coach is approximately 551 miles (888 km).

  2. Is there a way to reach Palermo from Milano without flying?

    You can choose the coach to travel this route. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
24/07
US$145
25/07
US$191
Today
US$120
27/07
US$106
28/07
US$106
29/07
US$106
30/07
US$106
31/07
US$111
busbud logoThe cheapest trip from Milano to Palermo was searched and found on 27 Jul 2025 with a price of US$106

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo as early as possible.

You can expect to pay from US$106 to US$258 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at US$106, which is on 2025-07-27.

Usually Flixbus (IT) will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Milano and Palermo!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Milano to Palermo, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Milano to Palermo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Milano to Palermo.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Will you be returning to Milano by bus?

Bus from Milano to Palermo

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular bus departures from Milano

Popular bus departures to Milano

Continue your journey from Palermo