Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Greenville Station | South Station (Train Terminal) | Cheapest | ||||
Amtrak + NextGen Acela | Train | Greenville Station | Boston Route 128, MA | Fastest | ||||
Amtrak + NextGen Acela | Train | Greenville Station | South Station (Train Terminal) | No tags | ||||
| Train | Greenville Station | South Station (Train Terminal) | No tags | ||||
Amtrak + NextGen Acela | Train | Greenville Station | South Station (Train Terminal) | No tags |
Last refresh of the prices: Yesterday at 10:04 AM EST.
Compare 2 ways to go from Greenville to Boston
Among the sustainable travel choices, the Bus stands out as a good way to reach Boston. The journey takes about 22 hours 55 minutes, and with fares starting at just $166, it presents an excellent value for a comfortable ride.
Train companies
Based on 5724 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the WiFi. Amtrak ticket prices on this trip start at $281
Frequently asked questions about travelling from Greenville, SC to Boston, MA, US by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Greenville to Boston?
The cheapest train tickets from Greenville to Boston start at $281. The average price for this train route is around $639. Busbud recommends booking your tickets in advance to increase your chances of getting the lowest possible price.
How long is the train ride from Greenville to Boston?
The average train trip from Greenville to Boston takes 20h 44m and covers 1275 km. The quickest train gets you there in 21h 35m and is operated by Amtrak.
Which train operators serve the Greenville to Boston route?
Several major train operators serve this route, with 6 trains available per day.
What are the earliest and latest departure times for the train from Greenville to Boston?
The earliest train from Greenville to Boston departs at 2:23am. The latest train departs at 2:23am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Greenville, SC to Boston, MA, US was searched and found on Jan 12, 2026 with a price of $216To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Greenville, SC to Boston, MA, US, as early as possible.
You can expect to pay from $216 to $1,394 for a train ticket from Greenville, SC to Boston, MA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $216 which is on 2026-01-12.
