Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Union Station | Bus station | Cheapest | |||||
 | Exxon, 2230 New York Av. NE | 2301 W Lucas St. | Fastest | |||||
| #3355 Benning Rd NE | 2301 W Lucas St. | No tags | |||||
 | Union Station | Florence, SC | No tags |
Accepted payments
Compare 2 ways to go from Washington to Florence
Busbud recommends taking the train from Washington to FlorenceAmong the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 7 hours 46 minutes, and with fares starting at just US$70, it presents an excellent value for a comfortable ride.
Bus Washington, DC, US to Florence, SC, US: Trip Overview
Compare bus companies
Washington to Florence Bus
Busbud helps you find a bus from Washington to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make sure you can find a bus service from Washington to Florence from the most reliable bus companies operating this trip.
Discover how much the bus trip from Washington to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Washington and Florence?
Frequently asked questions on the trip Washington, DC, US - Florence, SC, US
What is the travel distance from Washington to Florence?
It's about 572 km (355 miles) from Washington to Florence.
What are the departure and arrival locations for buses traveling from Washington to Florence?
Buses departing from Union Station in Washington will take you to Florence Bus Station in Florence.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Washington, DC, US to Florence, SC, US was searched and found on Sep 20, 2025 with a price of US$59To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Washington, DC, US to Florence, SC, US, as early as possible.
You can expect to pay from US$59 to US$110 for a bus ticket from Washington, DC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$59 which is on 2025-09-20.
Usually Wanda Coach will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Washington and Florence!
Start sightseeing the minute your bus leaves the station. If you're on the night bus from Washington to Florence, get comfy and count the stars.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Washington to Florence will emit less CO2 than a car or an airplane.
Tune out to the fine sounds of your best music playlist on your bus trip from Washington to Florence while indulging in miles on end of beautiful scenic views.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
What's the cheapest way to go from Washington, DC, US to Florence, SC, US?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Washington
Buses Leaving from Washington
- Bus from Washington to Washington
- Bus Washington - Washington
- Washington - Des Moines
- Bus from Washington to North East
- Bus Washington - Kingston
- Washington - Rochester
- Bus from Washington to Philadelphia
- Bus Washington - Atlanta
- Washington - Boston
- Bus from Washington to Virginia Beach
- Bus Washington - Greensboro
- Washington - Niagara Falls
- Bus from Washington to Richmond
- Bus Washington - Newark
- Washington - Baltimore
Buses Going to Washington
- Bus from Seattle to Washington
- Bus Bellingham - Washington
- Vancouver - Washington
- Bus from Salem to Washington
- Bus Salem - Washington
- Yakima - Washington
- Bus from Philadelphia to Washington
- Bus Buffalo - Washington
- Newark - Washington
- Bus from New Brunswick to Washington
- Bus Richmond - Washington
- Baltimore - Washington
- Bus from Youngstown to Washington
- Bus Allentown - Washington
- Chicago - Washington
Popular Buses Connecting Florence
Buses Leaving from Florence
- Bus from Florence to Kansas City
- Bus Florence - Kansas City
- Florence - Oklahoma City
- Bus from Florence to Montgomery
- Bus Florence - Jackson
- Florence - Washington
- Bus from Florence to Cincinnati
- Bus Florence - Chicago
- Florence - Manchester
- Bus from Florence to Miami
- Bus Florence - Columbus
- Florence - Easton
- Bus from Florence to Richmond
- Bus Florence - Clarksville
- Florence - Opelika
Buses Going to Florence
- Bus from Syracuse to Florence
- Bus Manchester - Florence
- Columbus - Florence
- Bus from Columbus to Florence
- Bus Los Angeles - Florence
- Toronto - Florence
- Bus from Greensboro to Florence
- Bus Portland - Florence
- Orlando - Florence
- Bus from Boston to Florence
- Bus New Haven - Florence
- West Palm Beach - Florence
- Bus from New York City to Florence
- Bus New Carrollton - Florence
- Durham - Florence
Popular routes in this country
- Bus from Boston to New York City
- Bus Washington - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Baton Rouge - New Orleans
- Bus from Albany to New York City
- Bus Los Angeles - San Francisco
- Miami - Orlando
- Bus from Los Angeles to San Diego
- Bus Las Vegas - Los Angeles
- Atlanta - Savannah