Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | Detroit Bus Station | CheapestFastest | ||||
| Bus | Tupelo (Brothers Quick Stop) | Detroit Bus Station | No tags |
Last refresh of the prices: Last Thursday at 7:29 PM CST.
Get from Tupelo to Detroit
The journey takes about 22 hours, and with fares starting at just $265, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87494 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $265
Frequently asked questions about travelling from Tupelo to Detroit, MI by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to Detroit?
The cheapest bus tickets from Tupelo to Detroit start from $265. The average price for this route is around $291. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to Detroit?
The average bus travel time from Tupelo to Detroit is 22h, covering a distance of 1025 km. The quickest bus can get you there in 22h and is operated by Greyhound.
Which bus companies service the Tupelo to Detroit route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Tupelo to Detroit?
The earliest bus departs from Tupelo to Detroit at 10:55am. And the latest bus departs at 9:35pm.
What are the CO₂ emissions for the bus trip from Tupelo to Detroit?
A bus trip from Tupelo to Detroit generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Detroit, MI was searched and found on Jan 14, 2026 with a price of $184To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Detroit, MI, as early as possible.
You can expect to pay from $184 to $254 for a bus ticket from Tupelo to Detroit, MI based on the last 2 days. You can expect to find the cheapest price for the trip at $184 which is on 2026-01-14.
