Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Salisbury (Citgo Fast Stop) | Chicago 95Th & Dan Ryan | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | Chicago 95Th & Dan Ryan | Fastest | ||||
| Bus | Salisbury (Citgo Fast Stop) | Downtown Greyhound Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Salisbury (Citgo Fast Stop) | Downtown Greyhound Station | No tags | ||||
| Bus | Salisbury (Citgo Fast Stop) | Downtown Greyhound Station | No tags |
Last refresh of the prices: Today at 3:38 PM EST.
Compare 2 ways to go from Salisbury to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 4 hours 5 minutes, and with fares starting at just $176, it presents an excellent value for a comfortable ride.
Where are the popular stops in Salisbury and Chicago?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
Based on 87449 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $176
Frequently asked questions about travelling from Salisbury, NC, US to Chicago by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Salisbury to Chicago?
The cheapest bus tickets from Salisbury to Chicago start from $176. The average price for this route is around $289. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Salisbury to Chicago?
The average bus travel time from Salisbury to Chicago is 1d 4h, covering a distance of 917 km. The quickest bus can get you there in 1d 2h and is operated by Greyhound.
Which bus companies service the Salisbury to Chicago route?
Several major bus companies operate on this route with 6 buses available per day.
What are the earliest and latest departure times for the bus from Salisbury to Chicago?
The earliest bus departs from Salisbury to Chicago at 6:15am. And the latest bus departs at 7:05pm.
What are the CO₂ emissions for the bus trip from Salisbury to Chicago?
A bus trip from Salisbury to Chicago generates an estimated 23 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Salisbury, NC, US to Chicago was searched and found on Dec 24, 2025 with a price of $166To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Salisbury, NC, US to Chicago, as early as possible.
You can expect to pay from $166 to $486 for a bus ticket from Salisbury, NC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at $178 which is on 2025-12-25.
What's the cheapest way to go from Salisbury, NC, US to Chicago?
The bus is the cheapest travel choice for this destination
