Bus Tickets from Orlando to Winston-Salem

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TodayJun 14
TomorrowJun 15
from US$176
MonJun 16
from US$123
TueJun 17
WedJun 18
ThuJun 19
from US$96
FriJun 20
SatJun 21

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 15 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 16 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 16 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Orlando
    Departure location: Orlando Bus Station
    Arrival time: June 16 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Orlando
    Departure location: The Florida Mall
    Arrival time: June 16 at
    Destination city: Winston-Salem
    Destination location: Winston Salem Greyhound Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Today at 12:51 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Compare 2 ways to go from Orlando to Winston-Salem

Average PriceUS$79 - US$235Average Duration16h 15m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$123 - US$123Average Duration1d 17h
77kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Orlando to Winston-Salem

Among the sustainable travel choices, the bus stands out as a good way to reach Winston-Salem. The journey takes about 16 hours 15 minutes, and with fares starting at just US$79, it presents an excellent value for a comfortable ride.

4bus per day
16h 15mAverage Duration
US$79Cheapest ticket
21kgCO₂ emissions

Bus Orlando to Winston-Salem: Trip Overview

Average Ticket PriceUS$152
Average Bus Trip Duration16h 15m
Number of daily buses4
Earliest bus departure5:15am
Distance858 km
Latest bus departure10:40pm

Orlando to Winston-Salem Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Orlando to Winston-Salem.

We make sure you can find a bus service from Orlando to Winston-Salem from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Winston-Salem from Orlando, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Orlando - Winston-Salem

  1. How long is the trip from Orlando to Winston-Salem by bus?

    The bus ride from Orlando to Winston-Salem takes 16h 15m, on average. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 16h.

  2. What is the travel distance from Orlando to Winston-Salem?

    Orlando and Winston-Salem are 849 km (527 miles) apart.

  3. What are the departure and arrival locations for buses traveling from Orlando to Winston-Salem?

    Buses departing from Orlando Bus Station in Orlando will take you to Winston Salem Greyhound Bus Station in Winston-Salem.

  4. What is the cheapest way to get from Orlando to Winston-Salem?

    If you're on a budget, consider traveling by bus to Winston-Salem from Orlando; it tends to be more affordable. With a starting ticket price of US$79, this bus becomes your top pick for this journey.

  5. How much does the bus ticket cost from Orlando to Winston-Salem?

    The bus from Orlando to Winston-Salem will cost you US$152, on average.

  6. Is there an overnight bus from Orlando to Winston-Salem?

    Yes! If you're heading from Orlando to Winston-Salem, you'll find buses departing until 10:40pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-12
No data
06-13
No data
Today
No data
06-15
No data
06-16
US$127
06-17
No data
06-18
No data
06-19
No data
busbud logoThe cheapest trip from Orlando to Winston-Salem was searched and found on Jun 16, 2025 with a price of US$127

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Orlando to Winston-Salem, as early as possible.

You can expect to pay from US$127 to US$127 for a bus ticket from Orlando to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at US$127 which is on 2025-06-16.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Orlando to Winston-Salem but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Orlando to Winston-Salem, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Orlando to Winston-Salem.

Make a music playlist for your bus ride from Orlando to Winston-Salem, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Orlando by bus?

Bus from Orlando to Winston-Salem

You can also go to Winston-Salem by train

Train from Orlando to Winston-Salem

Why choose Busbud?

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