Bus Tickets from Myrtle Beach to Indianapolis

Find affordable bus tickets from Myrtle Beach to Indianapolis with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayJun 15
from US$209
TomorrowJun 16
TueJun 17
WedJun 18
ThuJun 19
FriJun 20
SatJun 21
SunJun 22

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: June 15 at
    Departure city: Myrtle Beach
    Departure location: Bus Station
    Arrival time: June 16 at
    Destination city: Indianapolis
    Destination location: Downtown Transit Center
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: June 15 at
    Departure city: Myrtle Beach
    Departure location: Bus Station
    Arrival time: June 16 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 15 at
    Departure city: Myrtle Beach
    Departure location: Bus Station
    Arrival time: June 16 at
    Destination city: Indianapolis
    Destination location: Indianapolis Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 4:29 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Myrtle Beach to Indianapolis: Trip Overview

Average Ticket PriceUS$174
Average Bus Trip Duration1d 8h
Number of daily buses2
Earliest bus departure12:45pm
Distance932 km

Myrtle Beach to Indianapolis Bus

With Busbud, comparing and booking tickets for a bus from Myrtle Beach to Indianapolis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Myrtle Beach to Indianapolis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Indianapolis from Myrtle Beach, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Myrtle Beach - Indianapolis

  1. How long is the bus ride from Myrtle Beach to Indianapolis?

    The trip from Myrtle Beach to Indianapolis will take on average 1d 8h. If you're looking for the fastest way to get there, you'll find a bus doing the trip in about 1d 3h.

  2. How far is Myrtle Beach from Indianapolis?

    The distance between Myrtle Beach and Indianapolis is approximately 937 km (581 miles).

  3. What are the departure and arrival locations for buses traveling from Myrtle Beach to Indianapolis?

    Buses departing from Bus Station in Myrtle Beach will take you to Greyhound Amtrak Station in Indianapolis.

  4. What is the cheapest way to get from Myrtle Beach to Indianapolis?

    If you're on a budget, consider traveling by bus to Indianapolis from Myrtle Beach; it tends to be more affordable. With a starting ticket price of US$138, this bus becomes your top pick for this journey.

  5. How much does it cost to take the bus from Myrtle Beach to Indianapolis?

    You can expect to pay around US$174 for the bus ride from Myrtle Beach to Indianapolis.

  6. Can I take an overnight bus from Myrtle Beach to Indianapolis?

    Yes! If you're heading from Myrtle Beach to Indianapolis, you'll find buses departing until 12:45pm and arriving the next day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-13
No data
06-14
No data
Today
US$226
06-16
No data
06-17
No data
06-18
US$131
06-19
No data
06-20
No data
busbud logoThe cheapest trip from Myrtle Beach to Indianapolis was searched and found on Jun 18, 2025 with a price of US$131

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Myrtle Beach to Indianapolis, as early as possible.

You can expect to pay from US$131 to US$226 for a bus ticket from Myrtle Beach to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at US$131 which is on 2025-06-18.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from Myrtle Beach to Indianapolis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Myrtle Beach to Indianapolis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Myrtle Beach to Indianapolis.

Tune out to the fine sounds of your best music playlist on your bus trip from Myrtle Beach to Indianapolis while indulging in miles on end of beautiful scenic views.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Myrtle Beach by bus?

Bus from Myrtle Beach to Indianapolis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Myrtle Beach

Buses Leaving from Myrtle Beach

Buses Going to Myrtle Beach

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis