Next departures to La Crosse
One passenger / one way
- This trip is recommended because it is the: Cheapest + FastestDeparture time: June 27 atDeparture city: MadisonDeparture location: University of Wisconsin - Gordon CenterArrival time: June 27 atDestination city: La CrosseDestination location: 632 17th Street NorthOperated by: Jefferson Lines
Vehicle: BusDuration: - Departure time: June 27 atDeparture city: MadisonDeparture location: Dutch Mill Park & RideArrival time: June 27 atDestination city: La CrosseDestination location: La Crosse, WIOperated by: Amtrak
Vehicle: BusDuration: - Departure time: June 27 atDeparture city: MadisonDeparture location: Madison WI - Univ. of Wisc. Wisconsin Hist. Soc. (MSN)Arrival time: June 27 atDestination city: La CrosseDestination location: La Crosse WI - University of Wisconsin (LSW)Operated by: Megabus US
Vehicle: BusDuration: - Departure time: June 27 atDeparture city: MadisonDeparture location: University of Wisconsin - Gordon CenterArrival time: June 27 atDestination city: La CrosseDestination location: La Crosse MTU Transit CenterOperated by: Jefferson LinesVehicle: BusDuration:
- Departure time: June 27 atDeparture city: MadisonDeparture location: Dutch Mill Park & RideArrival time: June 27 atDestination city: La CrosseDestination location: La Crosse, WIOperated by: AmtrakVehicle: BusDuration:
Last refresh of the prices: Today at 12:20 AM CDT.
Prices and availability are subject to change.
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Bus Madison to La Crosse: Trip Overview
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Madison to La Crosse Bus
Busbud helps you find a bus from Madison to La Crosse. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Madison to La Crosse.
Whether it is cheap bus tickets or more luxurious buses going to La Crosse from Madison, we help you find what you're looking for based on how much of a budget you have.
Frequently asked questions on the trip Madison, WI - La Crosse, WI
What is the distance between Madison and La Crosse?
The distance between Madison and La Crosse is approximately 171 km (106 miles).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Madison to La Crosse was searched and found on Jun 25, 2025 with a price of US$25To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Madison to La Crosse, as early as possible.
You can expect to pay from US$25 to US$759 for a bus ticket from Madison to La Crosse based on the last 2 days. You can expect to find the cheapest price for the trip at US$25 which is on 2025-06-27.
Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Madison and La Crosse!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Madison to La Crosse.
Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Madison to La Crosse.
Make a music playlist for your bus ride from Madison to La Crosse, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!
Top travelled bus routes
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