Bus Tickets from La Crosse, WI to Milwaukee

Next departures

Next departures for La Crosse to Milwaukee on September 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Megabus US
La Crosse St Andrew St
Milwaukee Bus Station, St. Paul & N6th road.Cheapest
Megabus US
La Crosse WI - University of Wisconsin (LSW)
Milwaukee Bus Station, St. Paul & N6th road.Fastest
Megabus US
La Crosse WI - University of Wisconsin (LSW)
Milwaukee Bus Station, St. Paul & N6th road.No tags

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from La Crosse to Milwaukee

Bus
Average PriceUS$41 - US$57Average Duration4h 40m
7kg CO₂e5 out of 5 stars
Most eco-friendly
Train
Average PriceUS$27 - US$595Average Duration3h 36m
26kg CO₂e1 out of 5 stars
CheapestFastest
busbud logoBusbud recommends taking the train from La Crosse to Milwaukee

Among the sustainable travel choices, the train stands out as a good way to reach Milwaukee. The journey takes about 3 hours 36 minutes, and with fares starting at just US$27, it presents an excellent value for a comfortable ride.

5train per day
3h 36mAverage Duration
US$27Cheapest ticket
26kgCO₂ emissions

Bus La Crosse, WI to Milwaukee: Trip Overview

Average Ticket PriceUS$46
Average Bus Trip Duration4h 40m
Number of daily buses2
Earliest bus departure2:30pm
Distance283 km
Latest bus departure4:10pm

La Crosse to Milwaukee Bus

Busbud helps you find a bus from La Crosse to Milwaukee. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

Bus service from La Crosse to Milwaukee will be provided by the most trusted bus companies.

Whether it is cheap bus tickets or more luxurious buses going to Milwaukee from La Crosse, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip La Crosse, WI - Milwaukee

  1. What is the distance between La Crosse and Milwaukee?

    The distance between La Crosse and Milwaukee is approximately 284 km (176 miles).

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-31
US$43
09-01
US$43
Today
US$39
09-03
US$43
09-04
US$43
09-05
US$39
09-06
US$43
09-07
US$43
busbud logoThe cheapest trip from La Crosse, WI to Milwaukee was searched and found on Sep 2, 2025 with a price of US$39

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Crosse, WI to Milwaukee, as early as possible.

You can expect to pay from US$39 to US$54 for a bus ticket from La Crosse, WI to Milwaukee based on the last 2 days. You can expect to find the cheapest price for the trip at US$39 which is on 2025-09-05.

Usually Megabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between La Crosse and Milwaukee!

Much more than a mere vehicle taking you from La Crosse to Milwaukee, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from La Crosse to Milwaukee.

Make a music playlist for your bus ride from La Crosse to Milwaukee, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to La Crosse, WI by bus?

Bus from Milwaukee to La Crosse, WI

You can also go to Milwaukee by train

Train from La Crosse, WI to Milwaukee

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting La Crosse

Buses Leaving from La Crosse

Buses Going to La Crosse

Popular Buses Connecting Milwaukee

Buses Leaving from Milwaukee

Buses Going to Milwaukee