Bus from Lyon to Brussels: Tickets & Schedules

Next bus departures

Next departures for Lyon to Brussels on December 26
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
BlaBlaCar BusBus
    		Lyon - Perrache Bus Station
    		Brussels-South (Gare du Midi)Cheapest
    BlaBlaCar BusBus
      		Lyon - Perrache Bus Station
      		Brussels-South (Gare du Midi)Fastest
      BlaBlaCar BusBus
        		Lyon - Perrache Bus Station
        		Brussels-South (Gare du Midi)No tags
        FlixbusBus
        		Aéroport LYS
        		Brussels North Train StationNo tags
        BlaBlaCar BusBus
          		Lyon - Perrache Bus Station
          		Brussels-South (Gare du Midi)No tags

          Last refresh of the prices: Today at 6:28 AM CET.

          Compare 3 ways to go from Lyon to Brussels

          We recommend taking the train

          Among the sustainable travel choices, the train stands out as a good way to reach Brussels. The journey takes about 4 hours 13 minutes, and with fares starting at just $97, it presents an excellent value for a comfortable ride.

          19train per day
          4h 13mAverage Duration
          566 kmDistance
          14kgCO₂ emissions
          Bus
          		Average Price$35 - $277Average Duration11h 25m
          14kg CO₂e
          Train
          		Average Price$97 - $372Average Duration4h 13m
          14kg CO₂e
          Carpool
          		Average Price$57 - $151Average Duration7h 40m
          24kg CO₂e

          Frequently asked questions about travelling from Lyon to Brussels by bus

          Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

          1. How much is the bus ticket from Lyon to Brussels?

            The cheapest bus tickets from Lyon to Brussels start from $35. The average price for this route is around $64. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

          2. How long is the bus ride from Lyon to Brussels?

            The average bus travel time from Lyon to Brussels is 11h 25m, covering a distance of 570 km. The quickest bus can get you there in 8h 40m and is operated by BlaBlaCar Bus.

          3. Which bus companies service the Lyon to Brussels route?

            Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus, BlaBlaCar Bus.

          4. What are the earliest and latest departure times for the bus from Lyon to Brussels?

            The earliest bus departs from Lyon to Brussels at 12:10am. And the latest bus departs at 11:59pm.

          5. What are the CO₂ emissions for the bus trip from Lyon to Brussels?

            A bus trip from Lyon to Brussels generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

          6. What is the best bus company from Lyon to Brussels?

            According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11248 reviews.

          7. Which bus company has the best Wi-Fi from Lyon to Brussels?

            Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

          8. Which bus company has the best on-time performance from Lyon to Brussels?

            According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

          9. Which bus company has the cleanest buses from Lyon to Brussels?

            According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.

          Find cheapest prices for buses

          Price is for a one-way ticket for one passenger and based on past searches.

          Best price found
          12-23
          $119
          12-24
          $222
          Today
          $77
          12-26
          $90
          12-27
          $94
          12-28
          $102
          12-29
          $119
          12-30
          $103
          busbud logoThe cheapest trip from Lyon to Brussels was searched and found on Dec 25, 2025 with a price of $77

          To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Brussels, as early as possible.

          You can expect to pay from $77 to $254 for a bus ticket from Lyon to Brussels based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2025-12-26.

          Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

          What's the cheapest way to go from Lyon to Brussels?

          busbud logoThe bus is the cheapest travel choice for this destination

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