Bus Tickets from Jacksonville, FL to Charleston, SC, US

TodayAug 1
from US$51
TomorrowAug 2
from US$56
SunAug 3
from US$54
MonAug 4
from US$54
TueAug 5
from US$52
WedAug 6
from US$50
ThuAug 7
from US$52
FriAug 8
from US$56

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: August 2 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 2 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: August 2 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 2 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: August 2 at
    Departure city: Jacksonville
    Departure location: Jacksonville Bus Station
    Arrival time: August 2 at
    Destination city: Charleston
    Destination location: 4565 Gaynor Ave, North Charleston
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 12:13 AM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 3 ways to go from Jacksonville to Charleston

Bus
Average PriceUS$44 - US$58Average Duration5h 5m
8kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$51 - US$166Average Duration4h 14m
29kg CO₂e1 out of 5 stars
Fastest
Shuttle
Average PriceUS$91 - US$91Average Duration5h
9kg CO₂e4 out of 5 stars
busbud logoBusbud recommends taking the bus from Jacksonville to Charleston

Among the sustainable travel choices, the bus stands out as a good way to reach Charleston. The journey takes about 5 hours 5 minutes, and with fares starting at just US$44, it presents an excellent value for a comfortable ride.

1bus per day
5h 5mAverage Duration
US$44Cheapest ticket
8kgCO₂ emissions

Bus Jacksonville, FL to Charleston, SC, US: Trip Overview

Average Ticket PriceUS$50
Average Bus Trip Duration5h 5m
Number of daily buses1
Earliest bus departure8:45am
Distance324 km
Latest bus departure9:05am

Jacksonville to Charleston Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Jacksonville to Charleston.

We make sure you can find a bus service from Jacksonville to Charleston from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Charleston from Jacksonville, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Jacksonville, FL - Charleston, SC, US

  1. How far is Jacksonville from Charleston?

    It's about 318 km (198 miles) from Jacksonville to Charleston.

  2. What are the departure and arrival locations for buses traveling from Jacksonville to Charleston?

    Buses departing from Jacksonville Amtrak Station in Jacksonville will take you to Charleston Bus Station in Charleston.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-30
US$42
07-31
US$46
Today
US$43
08-02
US$48
08-03
US$46
08-04
US$46
08-05
US$44
08-06
US$42
busbud logoThe cheapest trip from Jacksonville, FL to Charleston, SC, US was searched and found on Jul 30, 2025 with a price of US$42

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Jacksonville, FL to Charleston, SC, US, as early as possible.

You can expect to pay from US$42 to US$72 for a bus ticket from Jacksonville, FL to Charleston, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$42 which is on 2025-08-06.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Jacksonville to Charleston but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Jacksonville to Charleston, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Jacksonville to Charleston.

Make a music playlist for your bus ride from Jacksonville to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

What's the cheapest way to go from Jacksonville, FL to Charleston, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Jacksonville, FL by bus?

Bus from Jacksonville, FL to Charleston, SC, US

You can also go to Charleston, SC, US by train

Train from Jacksonville, FL to Charleston, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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