Bus Tickets from Guadalajara, MX to Santa Ana, SON, MX

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Previously seen trips

One passenger / one way

  • Departure time: May 6 at
    Departure city: Guadalajara
    Departure location: Nueva Central
    Arrival time: May 7 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: May 6 at
    Departure city: Guadalajara
    Departure location: Nueva Central
    Arrival time: May 7 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: May 6 at
    Departure city: Guadalajara
    Departure location: Nueva Central
    Arrival time: May 7 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: June 5 at
    Departure city: Guadalajara
    Departure location: Zapopan Guadalajara
    Arrival time: June 6 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: June 5 at
    Departure city: Guadalajara
    Departure location: Zapopan Guadalajara
    Arrival time: June 6 at
    Destination city: Santa Ana
    Destination location: Santa Ana Col Del Rio
    Operated by: TufesaTufesa
    Vehicle: BusDuration:

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Bus Guadalajara, MX to Santa Ana, SON, MX: Trip Overview

Average Ticket PriceUS$156
Average Bus Trip Duration23h 20m
Number of daily buses6
Earliest bus departure9:00am
Distance1353 km
Latest bus departure4:30pm

Guadalajara to Santa Ana Bus

Busbud helps you find a bus from Guadalajara to Santa Ana. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Guadalajara to Santa Ana.

Discover how much the bus trip from Guadalajara to Santa Ana will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Guadalajara, MX - Santa Ana, SON, MX

  1. How far is Guadalajara from Santa Ana?

    The distance between Guadalajara and Santa Ana is approximately 1345 km (834 miles).

  2. What are the departure and arrival locations for buses traveling from Guadalajara to Santa Ana?

    Buses departing from Nueva Central in Guadalajara will take you to Parada de Autobuses de Santa Ana in Santa Ana.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08-25
No data
08-26
US$142
Today
No data
08-28
No data
08-29
No data
08-30
No data
08-31
US$145
09-01
No data
busbud logoThe cheapest trip from Guadalajara, MX to Santa Ana, SON, MX was searched and found on Aug 26, 2025 with a price of US$142

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guadalajara, MX to Santa Ana, SON, MX, as early as possible.

You can expect to pay from US$142 to US$145 for a bus ticket from Guadalajara, MX to Santa Ana, SON, MX based on the last 2 days. You can expect to find the cheapest price for the trip at US$145 which is on 2025-08-31.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Guadalajara and Santa Ana!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Guadalajara to Santa Ana.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Guadalajara to Santa Ana will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Guadalajara to Santa Ana while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Guadalajara, MX by bus?

Bus from Santa Ana, SON, MX to Guadalajara, MX

Why choose Busbud?

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