Bus Tickets from Florence, SC, US to Baltimore

Find affordable bus tickets from Florence, SC, US to Baltimore with flexible options. Book your trip now

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TodayJun 26
from US$80
TomorrowJun 27
from US$110
SatJun 28
from US$91
SunJun 29
MonJun 30
from US$104
TueJul 1
from US$82
WedJul 2
ThuJul 3
from US$99

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: June 27 at
    Departure city: Florence
    Departure location: 2301 W Lucas St.
    Arrival time: June 28 at
    Destination city: Baltimore
    Destination location: O'Donnell St. & Travel Plaza, Infront of TA Gas station
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: June 27 at
    Departure city: Florence
    Departure location: 2301 W Lucas St.
    Arrival time: June 28 at
    Destination city: Baltimore
    Destination location: O'Donnell St. & Travel Plaza, Infront of TA Gas station
    Operated by: Wanda CoachWanda Coach
    Vehicle: BusDuration:
  • Departure time: June 27 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: June 28 at
    Destination city: Baltimore
    Destination location: Baltimore Downtown Bus Station
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: June 27 at
    Departure city: Florence
    Departure location: Florence, SC
    Arrival time: June 27 at
    Destination city: Baltimore
    Destination location: Baltimore Downtown Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: June 27 at
    Departure city: Florence
    Departure location: Bus station
    Arrival time: June 28 at
    Destination city: Baltimore
    Destination location: Baltimore Bus Stop
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Friday at 5:50 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Florence to Baltimore

Bus
Average PriceUS$65 - US$188Average Duration10h 15m
16kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$82 - US$279Average Duration9h 27m
58kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Florence to Baltimore

Among the sustainable travel choices, the bus stands out as a good way to reach Baltimore. The journey takes about 10 hours 15 minutes, and with fares starting at just US$65, it presents an excellent value for a comfortable ride.

5bus per day
10h 15mAverage Duration
US$65Cheapest ticket
16kgCO₂ emissions

Bus Florence to Baltimore: Trip Overview

Average Ticket PriceUS$110
Average Bus Trip Duration10h 15m
Number of daily buses4.333333333333333
Earliest bus departure12:05am
Distance631 km
Latest bus departure11:59pm

Florence to Baltimore Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Florence to Baltimore.

We make it our job to connect you with the most dependable bus companies that cover bus service from Florence to Baltimore.

From cheap bus tickets to more luxurious buses travelling from Florence to Baltimore, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Florence, SC, US - Baltimore

  1. What is the travel distance from Florence to Baltimore?

    The distance between Florence and Baltimore is around 627 km (389 miles).

  2. What are the departure and arrival locations for buses traveling from Florence to Baltimore?

    Buses traveling this route start their trip at Florence Bus Station, in Florence, and end it at Baltimore Downtown Bus Station, in Baltimore.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06-24
US$77
06-25
US$72
Today
US$72
06-27
US$100
06-28
US$98
06-29
No data
06-30
US$100
07-01
US$74
busbud logoThe cheapest trip from Florence to Baltimore was searched and found on Jun 25, 2025 with a price of US$72

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence to Baltimore, as early as possible.

You can expect to pay from US$72 to US$117 for a bus ticket from Florence to Baltimore based on the last 2 days. You can expect to find the cheapest price for the trip at US$74 which is on 2025-07-01.

Usually iLIKEBUS, FlixBus Inc. will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Florence to Baltimore but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Florence to Baltimore.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Florence to Baltimore that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Florence to Baltimore.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Florence to Baltimore?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Florence by bus?

Bus from Florence to Baltimore

You can also go to Baltimore by train

Train from Florence to Baltimore

Why choose Busbud?

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