Bus Tickets from Des Moines to Knoxville, TN

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Previously seen trips

One passenger / one way

  • Departure time: April 8 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: April 9 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: June 12 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: June 13 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: July 31 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: August 1 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: August 1 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: August 2 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: August 2 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: August 3 at
    Destination city: Knoxville
    Destination location: Knoxville Bus Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

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Bus Des Moines to Knoxville, TN: Trip Overview

Average Ticket PriceUS$175
Average Bus Trip Duration1d 11h
Number of daily buses1
Earliest bus departure5:30am
Distance1047 km

Des Moines to Knoxville Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Des Moines to Knoxville.

We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to Knoxville.

From cheap bus tickets to more luxurious buses travelling from Des Moines to Knoxville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Des Moines - Knoxville, TN

  1. What is the travel distance from Des Moines to Knoxville?

    It's about 1049 km (650 miles) from Des Moines to Knoxville.

  2. What are the departure and arrival locations for buses traveling from Des Moines to Knoxville?

    Buses traveling this route start their trip at Jefferson/Trailways Depot, in Des Moines, and end it at 100 Kirkwood St, in Knoxville.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Des Moines to Knoxville but it'll also be endearing to native speakers who will surely appreciate your effort.

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Des Moines to Knoxville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Knoxville that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Des Moines to Knoxville.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Des Moines by bus?

Bus from Knoxville, TN to Des Moines

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