- Des Moines to Knoxville buses
Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
![]() | Bus | Des Moines (Subway) | Knoxville Bus Station | No tags | ||||
![]() | Bus | Des Moines (Subway) | Knoxville Bus Station | No tags | ||||
![]() | Bus | Des Moines (Subway) | Knoxville Bus Station | No tags | ||||
![]() | Bus | Des Moines | Knoxville Bus Station | No tags |
Get from Des Moines to Knoxville
The journey takes about 1 day, 8 hours 10 minutes, and with fares starting at just $197, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Knoxville?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $197
Frequently asked questions about travelling from Des Moines to Knoxville, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Des Moines to Knoxville?
The cheapest bus tickets from Des Moines to Knoxville start from $197. The average price for this route is around $210. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Des Moines to Knoxville?
The average bus travel time from Des Moines to Knoxville is 1d 8h, covering a distance of 1048 km. The quickest bus can get you there in 1d 8h and is operated by Greyhound.
Which bus companies service the Des Moines to Knoxville route?
Several major bus companies operate on this route with 1 buses available per day.
What are the earliest and latest departure times for the bus from Des Moines to Knoxville?
The earliest bus departs from Des Moines to Knoxville at 9:45am. And the latest bus departs at 9:45am.
What are the CO₂ emissions for the bus trip from Des Moines to Knoxville?
A bus trip from Des Moines to Knoxville generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.






