Trains leaving Saturday
One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: June 21 atDeparture city: HarrisburgDeparture location: Harrisburg, PAArrival time: June 22 atDestination city: St LouisDestination location: Gateway StationOperated by: Amtrak
Vehicle: TrainDuration:
Accepted payments
Compare 2 ways to go from Harrisburg to St Louis.
Busbud recommends taking the bus from Harrisburg to St LouisAmong the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 22 hours 5 minutes and with fares starting at just $117, it presents an excellent value for a comfortable ride.
Train Harrisburg to St Louis: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5214 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $279.00
Harrisburg to St Louis Train
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Discover how much the train trip from Harrisburg to St Louis will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.
Frequently asked questions for your trip Harrisburg - St Louis
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to St Louis was searched and found on Jun 21, 2025 with a price of $772To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Harrisburg to St Louis, as early as possible.
You can expect to pay from $772 to $772 for a train ticket from Harrisburg to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $772 which is on 2025-06-21.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Harrisburg to St Louis is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Whether you take a regional or high-speed train to St Louis, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
With up to 30x less CO2 emissions for your train journey between Harrisburg and St Louis, the train is an ecological alternative to flights or personal cars.
Make a music playlist for your train ride from Harrisburg to St Louis, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.
Top Traveled Train Routes
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