Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Brussels South/Midi Train Station | Hlavní nádraží | CheapestFastest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags |
Last refresh of the prices: Last Saturday at 9:37 AM CET.
Compare 2 ways to go from Brussels to Prague
Among the sustainable travel choices, the bus stands out as the good way to reach Prague. The journey takes about 19 hours 15 minutes and with fares starting at just $45, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Brussels and Prague?
Brussels
- ABoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- BRue de France 85, 1060 Saint-Gilles, Belgium
- C
Bruxelles / Brussels Central
Brussel-Centraal, Carrefour de l'Europe, 1000 Bruxelles, Belgium
Prague
- A300/8 Wilsonova, 110 00 Praha, Czechia
- BKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- CAviatická, 161 08, Praha 6, Czechia
- D
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - EChlumecká, 198 00 Praha 20, Czech Republic
- FTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Train Companies
Based on 6 reviews, the company was rated 3.8 stars on Busbud. Travelers were especially satisfied with the power outlets and the ticket access but often complained with the timeliness. Deutsche Bahn ticket prices on this trip start at $238
Frequently asked questions about traveling from Brussels to Prague by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Brussels to Prague?
The cheapest train tickets from Brussels to Prague start from $64. The average price for this train route is around $167. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Brussels to Prague?
The average train ride duration from Brussels to Prague is 14h 36m, covering a distance of 446 miles (718 km). The quickest train can get you there in 12h 47m and is operated by Deutsche Bahn.
Which train operators service the Brussels to Prague route?
Several major train operators operate on this route with 4 trains available per day.
What is the earliest and latest departure time for the train from Brussels to Prague?
The earliest train departs from Brussels to Prague at 6:01am. And the latest train departs at 10:01pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Prague was searched and found on Dec 15, 2025 with a price of $157To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague, as early as possible.
You can expect to pay from $157 to $1,143 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $181 which is on 2025-12-19.
Top Traveled Train Routes
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