Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Brussels South/Midi Train Station | Hlavní nádraží | CheapestFastest | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags | ||||
| Train | Brussels South/Midi Train Station | Hlavní nádraží | No tags |
Last refresh of the prices: Yesterday at 8:47 PM CET.
Compare 2 ways to go from Brussels to Prague
Among the sustainable travel choices, the Bus stands out as a good way to reach Prague. The journey takes about 19 hours 15 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Brussels and Prague?
Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- C
Bruxelles / Brussels Central
Brussel-Centraal, Carrefour de l'Europe, 1000 Bruxelles, Belgium
Prague
- A300/8 Wilsonova, 110 00 Praha, Czechia
- B
Praha hl.n
Prague Main Railway Station, 120 00 Praha-Praha 2, Czechia - CKřižíkova 2b, Nové Město, 186 00 Praha-Praha 8, Czech Republic
- DAviatická, 161 08, Praha 6, Czechia
- EChlumecká, 198 00 Praha 20, Czech Republic
- FTomíčkova 2234, Chodov, 148 00 Praha-Praha 11, Czechia
Train Companies
Based on 8 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the power outlets and the ticket access but often complained with the timeliness. Deutsche Bahn ticket prices on this trip start at $238
Frequently asked questions about traveling from Brussels to Prague by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Brussels to Prague?
The cheapest train tickets from Brussels to Prague start from $92. The average price for this train route is around $121. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Brussels to Prague?
The average train ride duration from Brussels to Prague is 15h 29m, covering a distance of 446 miles (718 km). The quickest train can get you there in 12h 47m and is operated by Deutsche Bahn.
Which train operators service the Brussels to Prague route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Brussels to Prague?
The earliest train departs from Brussels to Prague at 6:22pm. And the latest train departs at 8:24pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Prague was searched and found on Feb 4, 2026 with a price of $133To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Brussels to Prague, as early as possible.
You can expect to pay from $133 to $832 for a train ticket from Brussels to Prague based on the last 2 days. You can expect to find the cheapest price for the trip at $133 which is on 2026-02-04.
