Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tijuana - Plaza El Mexicano | Santa Ana Bus Station | Cheapest | ||||
 | Bus | Tijuana Rtno Sentri | Santa Ana E Santa Ana Blvd | Fastest | ||||
Greyhound Lines Mexico + FlixBus | Bus | Tijuana - Plaza El Mexicano | Anaheim Regional Transportation Intermodal Center | No tags | ||||
| Bus | Tijuana - Plaza El Mexicano | Anaheim Regional Transportation Intermodal Center | No tags | ||||
| Bus | Tijuana Rtno Sentri | Santa Ana E Santa Ana Blvd | No tags |
Last refresh of the prices: Today at 7:56 AM PST.
Compare 2 ways to go from Tijuana to Santa Ana
Among the sustainable travel choices, the Bus stands out as the good way to reach Santa Ana. The journey takes about 5 hours 55 minutes and with fares starting at just $25, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$25 - $60 | Average Duration5h 55m | 4kg CO₂e | ||
Carpool | Average Price$5 - $5 | Average Duration1h 50m | 7kg CO₂e |
Where are the popular stops in Tijuana and Santa Ana?
Stops in Tijuana
- B
Terminal Tijuana Línea de Autobuses (ABC)
Frontera 26, Zona Urbana Rio Tijuana, 22010 Tijuana, B.C., Mexico - C
Central de Autobuses
Lázaro Cárdenas 15751, Chapultepec Alamar, 22110 Tijuana, B.C., Mexico - D
Buenavista
Calzada Juan Ojeda Robles 117-B, Col. Guadalupe Victoria, Buenavista Postal, Buena Vista, 22415 Tijuana, B.C. - E
Otay
Plaza Centrum Local 9, 2° Eje Oriente-Poniente No 208 - Ciudad Industrial Nueva, 22046 Tijuana - FCalle Ing. Juan Ojeda Robles 1140, Chapultepec Alamar, 22110 Tijuana, B.C., Mexico
Stops in Santa Ana
- A
Santa Ana Greyhound Bus Station
1000 E Santa Ana Blvd, Santa Ana, CA 92701 - B
602 S Main St
602 S Main St, Santa Ana, CA 92701, USA
Compare bus companies
Frequently asked questions about traveling from Tijuana to Santa Ana, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tijuana to Santa Ana?
The cheapest bus tickets from Tijuana to Santa Ana start from $25. The average price for this route is around $45. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tijuana to Santa Ana?
The average bus trip duration from Tijuana to Santa Ana is 5h 55m, covering a distance of 100 miles (161 km). The quickest bus can get you there in 3h and is operated by Los Limousines.
Which bus companies service the Tijuana to Santa Ana route?
Several major bus companies operate on this route with 54 buses available per day, including services from Los Limousines, Greyhound, Autotravel.
What is the earliest and latest departure time for the bus from Tijuana to Santa Ana?
The earliest bus departs from Tijuana to Santa Ana at 12:00am. And the latest bus departs at 10:30pm.
What are the CO₂ emissions for the bus trip from Tijuana to Santa Ana?
A bus trip from Tijuana to Santa Ana generates an estimated 4 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Tijuana to Santa Ana?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87463 reviews.
Which bus company has the best Wi-Fi from Tijuana to Santa Ana?
Based on reviews on Busbud, the bus company Los Limousines has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Tijuana to Santa Ana?
According to Busbud traveller reviews, the most timely bus company on this route is Greyhound, with a punctuality rating of 2.9 out of 5 stars.
Which bus company has the cleanest buses from Tijuana to Santa Ana?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Los Limousines, with a cleanliness rating of 3.9 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tijuana to Santa Ana, US was searched and found on Jan 13, 2026 with a price of $17To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tijuana to Santa Ana, US, as early as possible.
You can expect to pay from $17 to $42 for a bus ticket from Tijuana to Santa Ana, US based on the last 2 days. You can expect to find the cheapest price for the trip at $17 which is on 2026-01-13.
Usually Los Limousines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
